Effects of conditioning on the left ventricular function of young purebred Arabian horses
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1371/journal.pone.0304724 https://hdl.handle.net/11449/300323 |
Resumo: | The effects of conditioning on cardiac function in young horses is still unknown. For this reason, this study evaluated the left ventricular (LV) function of young horses by echocardiography after six weeks of conditioning. Fourteen untrained young purebred Arabian horses were evaluated at rest and after a stress test (ST) before and after a six-week conditioning program. There was an increase in V4 (p < 0.001) after conditioning, as well as a reduction in both heart rate (HR) at rest and peak HR during the ST (p < 0.001). There was also a reduction in internal diameter, along with an increase in interventricular septal, free wall and mean thicknesses and LV mass (p < 0.05). After the ST, the conditioned animals showed higher values of velocity time integral, stroke volume, systolic and cardiac indices, ejection (ET) and deceleration times (DT), end-diastolic volume, time to onset of radial myocardial velocity during early diastole and time to peak of transmitral flow velocity, in addition to reduced pre-ejection period (PEP), PEP/ET ratio and mean velocity of circumferential fiber shortening (p < 0.05). The conditioning protocol promoted physiological adaptations that indicate an improvement in the animals’ aerobic capacity associated with an enhanced left ventricular function. |
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Effects of conditioning on the left ventricular function of young purebred Arabian horsesThe effects of conditioning on cardiac function in young horses is still unknown. For this reason, this study evaluated the left ventricular (LV) function of young horses by echocardiography after six weeks of conditioning. Fourteen untrained young purebred Arabian horses were evaluated at rest and after a stress test (ST) before and after a six-week conditioning program. There was an increase in V4 (p < 0.001) after conditioning, as well as a reduction in both heart rate (HR) at rest and peak HR during the ST (p < 0.001). There was also a reduction in internal diameter, along with an increase in interventricular septal, free wall and mean thicknesses and LV mass (p < 0.05). After the ST, the conditioned animals showed higher values of velocity time integral, stroke volume, systolic and cardiac indices, ejection (ET) and deceleration times (DT), end-diastolic volume, time to onset of radial myocardial velocity during early diastole and time to peak of transmitral flow velocity, in addition to reduced pre-ejection period (PEP), PEP/ET ratio and mean velocity of circumferential fiber shortening (p < 0.05). The conditioning protocol promoted physiological adaptations that indicate an improvement in the animals’ aerobic capacity associated with an enhanced left ventricular function.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Veterinary Clinics and Surgery School of Agricultural and Veterinary Sciences São Paulo State University (UNESP), JaboticabalDepartment of Veterinary Clinics State University of Londrina, ParanáDepartment of Veterinary Clinics and Surgery School of Agricultural and Veterinary Sciences São Paulo State University (UNESP), JaboticabalFAPESP: 2020/11223-4FAPESP: 2021/06368-6Universidade Estadual Paulista (UNESP)Universidade Estadual de Londrina (UEL)Ramos, Gabriel Vieira [UNESP]Santos, Maíra Moreira [UNESP]Gava, Fábio Nelsonde Lacerda-Neto, José Corrêa [UNESP]2025-04-29T18:49:15Z2024-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1371/journal.pone.0304724PLoS ONE, v. 19, n. 6 June, 2024.1932-6203https://hdl.handle.net/11449/30032310.1371/journal.pone.03047242-s2.0-85195005698Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPLoS ONEinfo:eu-repo/semantics/openAccess2025-04-30T13:41:30Zoai:repositorio.unesp.br:11449/300323Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462025-04-30T13:41:30Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Effects of conditioning on the left ventricular function of young purebred Arabian horses |
title |
Effects of conditioning on the left ventricular function of young purebred Arabian horses |
spellingShingle |
Effects of conditioning on the left ventricular function of young purebred Arabian horses Ramos, Gabriel Vieira [UNESP] |
title_short |
Effects of conditioning on the left ventricular function of young purebred Arabian horses |
title_full |
Effects of conditioning on the left ventricular function of young purebred Arabian horses |
title_fullStr |
Effects of conditioning on the left ventricular function of young purebred Arabian horses |
title_full_unstemmed |
Effects of conditioning on the left ventricular function of young purebred Arabian horses |
title_sort |
Effects of conditioning on the left ventricular function of young purebred Arabian horses |
author |
Ramos, Gabriel Vieira [UNESP] |
author_facet |
Ramos, Gabriel Vieira [UNESP] Santos, Maíra Moreira [UNESP] Gava, Fábio Nelson de Lacerda-Neto, José Corrêa [UNESP] |
author_role |
author |
author2 |
Santos, Maíra Moreira [UNESP] Gava, Fábio Nelson de Lacerda-Neto, José Corrêa [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Universidade Estadual de Londrina (UEL) |
dc.contributor.author.fl_str_mv |
Ramos, Gabriel Vieira [UNESP] Santos, Maíra Moreira [UNESP] Gava, Fábio Nelson de Lacerda-Neto, José Corrêa [UNESP] |
description |
The effects of conditioning on cardiac function in young horses is still unknown. For this reason, this study evaluated the left ventricular (LV) function of young horses by echocardiography after six weeks of conditioning. Fourteen untrained young purebred Arabian horses were evaluated at rest and after a stress test (ST) before and after a six-week conditioning program. There was an increase in V4 (p < 0.001) after conditioning, as well as a reduction in both heart rate (HR) at rest and peak HR during the ST (p < 0.001). There was also a reduction in internal diameter, along with an increase in interventricular septal, free wall and mean thicknesses and LV mass (p < 0.05). After the ST, the conditioned animals showed higher values of velocity time integral, stroke volume, systolic and cardiac indices, ejection (ET) and deceleration times (DT), end-diastolic volume, time to onset of radial myocardial velocity during early diastole and time to peak of transmitral flow velocity, in addition to reduced pre-ejection period (PEP), PEP/ET ratio and mean velocity of circumferential fiber shortening (p < 0.05). The conditioning protocol promoted physiological adaptations that indicate an improvement in the animals’ aerobic capacity associated with an enhanced left ventricular function. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-06-01 2025-04-29T18:49:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1371/journal.pone.0304724 PLoS ONE, v. 19, n. 6 June, 2024. 1932-6203 https://hdl.handle.net/11449/300323 10.1371/journal.pone.0304724 2-s2.0-85195005698 |
url |
http://dx.doi.org/10.1371/journal.pone.0304724 https://hdl.handle.net/11449/300323 |
identifier_str_mv |
PLoS ONE, v. 19, n. 6 June, 2024. 1932-6203 10.1371/journal.pone.0304724 2-s2.0-85195005698 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
PLoS ONE |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
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1834482411615813632 |