Automated verification of care pathways using constraint programming

Detalhes bibliográficos
Autor(a) principal: Figueiredo, Renan Pereira de
Data de Publicação: 2019
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da Universidade Federal do Ceará (UFC)
Texto Completo: http://www.repositorio.ufc.br/handle/riufc/47937
Resumo: Clinical Pathways are used to standardize medical treatments. Specialists define these pathways using process-like notations that can ultimately be translated to formally defined languages. Bad construction of modeled care pathways can lead to satisfiability problems during the pathway execution. These problems can ultimately result in medical errors and need to be checked as formally as possible. Therefore, this study proposes a set of algorithms using a free open-source library dedicated to constraint programming allied with a DSL to encode and verify care pathways, checking four possible problems: states in deadlock, non-determinism, inaccessible steps and transitions with logically equivalent guard conditions. We then test our algorithms in 113 real care pathways used both in hospitals and surgeries. Using our algorithms, we were able to find 295 problems taking less than 1 second to complete the verification on most pathways.
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spelling Figueiredo, Renan Pereira deFerreira Filho, João Bosco2019-11-26T18:54:42Z2019-11-26T18:54:42Z2019FIGUEIREDO, Renan Pereira de. Automated verification of care pathways using constraint programming. 2019. 97 f. Dissertação (Mestrado em Ciência da Computação) - Universidade Federal do Ceará, Fortaleza, 2019.http://www.repositorio.ufc.br/handle/riufc/47937Clinical Pathways are used to standardize medical treatments. Specialists define these pathways using process-like notations that can ultimately be translated to formally defined languages. Bad construction of modeled care pathways can lead to satisfiability problems during the pathway execution. These problems can ultimately result in medical errors and need to be checked as formally as possible. Therefore, this study proposes a set of algorithms using a free open-source library dedicated to constraint programming allied with a DSL to encode and verify care pathways, checking four possible problems: states in deadlock, non-determinism, inaccessible steps and transitions with logically equivalent guard conditions. We then test our algorithms in 113 real care pathways used both in hospitals and surgeries. Using our algorithms, we were able to find 295 problems taking less than 1 second to complete the verification on most pathways.Protocolos clínicos são usados para padronizar tratamentos médicos. Os especialistas definem esses protocolos usando notações de processos, que podem ser traduzidas para linguagens formalmente definidas. A má construção desses protocolos clínicos modelados pode ocasionar em problemas de satisfatibilidade durante a execução do protocolo. Esses problemas podem resultar em erros médicos e precisam ser verificados o mais formalmente possível. Portanto, este estudo propõe um conjunto de algoritmos, utilizando uma biblioteca de código aberto gratuita dedicada à programação de restrições aliada a uma DSL para codificar e verificar os protocolos clínicos, verificando quatro possíveis problemas: estados em deadlock, não determinismo, passos inacessíveis e transições com condições de guarda logicamente equivalentes. Em seguida, testamos nossos algoritmos em um conjunto com 113 protocolos clpínicos reais usados em hospitais e cirurgias. Usando nossos algoritmos, conseguimos encontrar 295 problemas, sendo necessário menos de 1 segundo para concluir a verificação na maioria dos protocolos.Clinical pathwayConstraint programmingData-dependent transition systemDSLSatisfiability problemsAutomated verification of care pathways using constraint programmingAutomated verification of care pathways using constraint programminginfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisporreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccessORIGINAL2019_dis_rpfigueiredo.pdf2019_dis_rpfigueiredo.pdfapplication/pdf3897703http://repositorio.ufc.br/bitstream/riufc/47937/3/2019_dis_rpfigueiredo.pdf2e457178f61386f3c70bf21864d5404dMD53LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.ufc.br/bitstream/riufc/47937/4/license.txt8a4605be74aa9ea9d79846c1fba20a33MD54riufc/479372019-11-26 15:54:43.406oai:repositorio.ufc.br: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Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2019-11-26T18:54:43Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.pt_BR.fl_str_mv Automated verification of care pathways using constraint programming
dc.title.en.pt_BR.fl_str_mv Automated verification of care pathways using constraint programming
title Automated verification of care pathways using constraint programming
spellingShingle Automated verification of care pathways using constraint programming
Figueiredo, Renan Pereira de
Clinical pathway
Constraint programming
Data-dependent transition system
DSL
Satisfiability problems
title_short Automated verification of care pathways using constraint programming
title_full Automated verification of care pathways using constraint programming
title_fullStr Automated verification of care pathways using constraint programming
title_full_unstemmed Automated verification of care pathways using constraint programming
title_sort Automated verification of care pathways using constraint programming
author Figueiredo, Renan Pereira de
author_facet Figueiredo, Renan Pereira de
author_role author
dc.contributor.author.fl_str_mv Figueiredo, Renan Pereira de
dc.contributor.advisor1.fl_str_mv Ferreira Filho, João Bosco
contributor_str_mv Ferreira Filho, João Bosco
dc.subject.por.fl_str_mv Clinical pathway
Constraint programming
Data-dependent transition system
DSL
Satisfiability problems
topic Clinical pathway
Constraint programming
Data-dependent transition system
DSL
Satisfiability problems
description Clinical Pathways are used to standardize medical treatments. Specialists define these pathways using process-like notations that can ultimately be translated to formally defined languages. Bad construction of modeled care pathways can lead to satisfiability problems during the pathway execution. These problems can ultimately result in medical errors and need to be checked as formally as possible. Therefore, this study proposes a set of algorithms using a free open-source library dedicated to constraint programming allied with a DSL to encode and verify care pathways, checking four possible problems: states in deadlock, non-determinism, inaccessible steps and transitions with logically equivalent guard conditions. We then test our algorithms in 113 real care pathways used both in hospitals and surgeries. Using our algorithms, we were able to find 295 problems taking less than 1 second to complete the verification on most pathways.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-11-26T18:54:42Z
dc.date.available.fl_str_mv 2019-11-26T18:54:42Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv FIGUEIREDO, Renan Pereira de. Automated verification of care pathways using constraint programming. 2019. 97 f. Dissertação (Mestrado em Ciência da Computação) - Universidade Federal do Ceará, Fortaleza, 2019.
dc.identifier.uri.fl_str_mv http://www.repositorio.ufc.br/handle/riufc/47937
identifier_str_mv FIGUEIREDO, Renan Pereira de. Automated verification of care pathways using constraint programming. 2019. 97 f. Dissertação (Mestrado em Ciência da Computação) - Universidade Federal do Ceará, Fortaleza, 2019.
url http://www.repositorio.ufc.br/handle/riufc/47937
dc.language.iso.fl_str_mv por
language por
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eu_rights_str_mv openAccess
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instname:Universidade Federal do Ceará (UFC)
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instname_str Universidade Federal do Ceará (UFC)
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institution UFC
reponame_str Repositório Institucional da Universidade Federal do Ceará (UFC)
collection Repositório Institucional da Universidade Federal do Ceará (UFC)
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