Prevalence of hepatitis C virus infection and HCV genotypes among hemophiliacs in the State of Bahia, Northeastern Brazil: analysis of serological and virological parameters

Bibliographic Details
Main Author: Paraná, Raymundo
Publication Date: 2005
Other Authors: Reis, Galvão dos, Silva, Luciano Kalabric, Silva, Maria Betânia Souza da, Lopes, Gisele Barreto, Rodart, Itatiana Ferreira, Costa, Fernando Quadros, Santana, Nelma Pereira de, Santana, Aurelino
Format: Article
Language: eng
Source: Repositório Institucional da UFBA
Download full: http://repositorio.ufba.br/ri/handle/ri/13490
Summary: p.496-502
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spelling Paraná, RaymundoReis, Galvão dosSilva, Luciano KalabricSilva, Maria Betânia Souza daLopes, Gisele BarretoRodart, Itatiana FerreiraCosta, Fernando QuadrosSantana, Nelma Pereira deSantana, AurelinoParaná, RaymundoReis, Galvão dosSilva, Luciano KalabricSilva, Maria Betânia Souza daLopes, Gisele BarretoRodart, Itatiana FerreiraCosta, Fernando QuadrosSantana, Nelma Pereira deSantana, Aurelino2013-11-01T19:13:53Z2013-11-01T19:13:53Z20050037-8682http://repositorio.ufba.br/ri/handle/ri/13490v.38 n. 6p.496-502The objective of the present study was to analyze HCV serological and virological parameters from hemophiliacs in the State of Bahia. Anti-HCV was investigated by ELISA in a cohort of 268 hemophiliacs A/B who were followed-up in a reference unit for hemotherapy in the State of Bahia. HCV viremia and genotypes were also determined from a subset of 66 anti-HCV seropositive hemophiliacs. Seroprevalence among hemophiliacs was 42.2% (95% CI 36.5-48.1) and was significantly higher (p<0.05) according to age >10 years, presence of factor VIII/IX inhibitory antibodies and other infection markers. None of the hemophiliacs less than 5 years of age were anti-HCV seropositive. Viremia was detectable in 77.3% (51/66). HCV genotype 1 (74%) was the most prevalent followed by genotype 3 (22%) and genotype 2 (4%). Our results indicate that HCV prevalence is still high among hemophiliacs, although HCV transmission was not observed in young hemophiliacs.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2013-11-01T12:19:31Z No. of bitstreams: 1 a10v38n6.pdf: 385910 bytes, checksum: 1954463d6ebba96747ebf16f2a6f7d12 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-01T19:13:52Z (GMT) No. of bitstreams: 1 a10v38n6.pdf: 385910 bytes, checksum: 1954463d6ebba96747ebf16f2a6f7d12 (MD5)Made available in DSpace on 2013-11-01T19:13:53Z (GMT). No. of bitstreams: 1 a10v38n6.pdf: 385910 bytes, checksum: 1954463d6ebba96747ebf16f2a6f7d12 (MD5) Previous issue date: 2005http://dx.doi.org/10.1590/S0037-86822005000600010reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAHepatitis C virusHemophiliaPrevalenceGenotypeBahiaPrevalence of hepatitis C virus infection and HCV genotypes among hemophiliacs in the State of Bahia, Northeastern Brazil: analysis of serological and virological parametersRevista da Sociedade Brasileira de Medicina Tropicalinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBrasilinfo:eu-repo/semantics/openAccessengORIGINALa10v38n6.pdfa10v38n6.pdfapplication/pdf385910https://repositorio.ufba.br/bitstream/ri/13490/1/a10v38n6.pdf1954463d6ebba96747ebf16f2a6f7d12MD51LICENSElicense.txtlicense.txttext/plain1383https://repositorio.ufba.br/bitstream/ri/13490/2/license.txt05eca2f01d0b3307819d0369dab18a34MD52TEXTa10v38n6.pdf.txta10v38n6.pdf.txtExtracted texttext/plain36111https://repositorio.ufba.br/bitstream/ri/13490/3/a10v38n6.pdf.txtf1839cc5978ed78350b788cf7db67441MD53ri/134902022-08-08 13:19:38.075oai:repositorio.ufba.br:ri/13490VGVybW8gZGUgTGljZW7Dp2EsIG7Do28gZXhjbHVzaXZvLCBwYXJhIG8gZGVww7NzaXRvIG5vIFJlcG9zaXTDs3JpbyBJbnN0aXR1Y2lvbmFsIGRhIFVGQkEuCgogUGVsbyBwcm9jZXNzbyBkZSBzdWJtaXNzw6NvIGRlIGRvY3VtZW50b3MsIG8gYXV0b3Igb3Ugc2V1IHJlcHJlc2VudGFudGUgbGVnYWwsIGFvIGFjZWl0YXIgCmVzc2UgdGVybW8gZGUgbGljZW7Dp2EsIGNvbmNlZGUgYW8gUmVwb3NpdMOzcmlvIEluc3RpdHVjaW9uYWwgZGEgVW5pdmVyc2lkYWRlIEZlZGVyYWwgZGEgQmFoaWEgCm8gZGlyZWl0byBkZSBtYW50ZXIgdW1hIGPDs3BpYSBlbSBzZXUgcmVwb3NpdMOzcmlvIGNvbSBhIGZpbmFsaWRhZGUsIHByaW1laXJhLCBkZSBwcmVzZXJ2YcOnw6NvLiAKRXNzZXMgdGVybW9zLCBuw6NvIGV4Y2x1c2l2b3MsIG1hbnTDqm0gb3MgZGlyZWl0b3MgZGUgYXV0b3IvY29weXJpZ2h0LCBtYXMgZW50ZW5kZSBvIGRvY3VtZW50byAKY29tbyBwYXJ0ZSBkbyBhY2Vydm8gaW50ZWxlY3R1YWwgZGVzc2EgVW5pdmVyc2lkYWRlLgoKIFBhcmEgb3MgZG9jdW1lbnRvcyBwdWJsaWNhZG9zIGNvbSByZXBhc3NlIGRlIGRpcmVpdG9zIGRlIGRpc3RyaWJ1acOnw6NvLCBlc3NlIHRlcm1vIGRlIGxpY2Vuw6dhIAplbnRlbmRlIHF1ZToKCiBNYW50ZW5kbyBvcyBkaXJlaXRvcyBhdXRvcmFpcywgcmVwYXNzYWRvcyBhIHRlcmNlaXJvcywgZW0gY2FzbyBkZSBwdWJsaWNhw6fDtWVzLCBvIHJlcG9zaXTDs3Jpbwpwb2RlIHJlc3RyaW5naXIgbyBhY2Vzc28gYW8gdGV4dG8gaW50ZWdyYWwsIG1hcyBsaWJlcmEgYXMgaW5mb3JtYcOnw7VlcyBzb2JyZSBvIGRvY3VtZW50bwooTWV0YWRhZG9zIGVzY3JpdGl2b3MpLgoKIERlc3RhIGZvcm1hLCBhdGVuZGVuZG8gYW9zIGFuc2Vpb3MgZGVzc2EgdW5pdmVyc2lkYWRlIGVtIG1hbnRlciBzdWEgcHJvZHXDp8OjbyBjaWVudMOtZmljYSBjb20gCmFzIHJlc3RyacOnw7VlcyBpbXBvc3RhcyBwZWxvcyBlZGl0b3JlcyBkZSBwZXJpw7NkaWNvcy4KCiBQYXJhIGFzIHB1YmxpY2HDp8O1ZXMgc2VtIGluaWNpYXRpdmFzIHF1ZSBzZWd1ZW0gYSBwb2zDrXRpY2EgZGUgQWNlc3NvIEFiZXJ0bywgb3MgZGVww7NzaXRvcyAKY29tcHVsc8OzcmlvcyBuZXNzZSByZXBvc2l0w7NyaW8gbWFudMOqbSBvcyBkaXJlaXRvcyBhdXRvcmFpcywgbWFzIG1hbnTDqm0gYWNlc3NvIGlycmVzdHJpdG8gCmFvIG1ldGFkYWRvcyBlIHRleHRvIGNvbXBsZXRvLiBBc3NpbSwgYSBhY2VpdGHDp8OjbyBkZXNzZSB0ZXJtbyBuw6NvIG5lY2Vzc2l0YSBkZSBjb25zZW50aW1lbnRvCiBwb3IgcGFydGUgZGUgYXV0b3Jlcy9kZXRlbnRvcmVzIGRvcyBkaXJlaXRvcywgcG9yIGVzdGFyZW0gZW0gaW5pY2lhdGl2YXMgZGUgYWNlc3NvIGFiZXJ0by4KRepositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestrepositorio@ufba.bropendoar:19322022-08-08T16:19:38Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Prevalence of hepatitis C virus infection and HCV genotypes among hemophiliacs in the State of Bahia, Northeastern Brazil: analysis of serological and virological parameters
dc.title.alternative.pt_BR.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical
title Prevalence of hepatitis C virus infection and HCV genotypes among hemophiliacs in the State of Bahia, Northeastern Brazil: analysis of serological and virological parameters
spellingShingle Prevalence of hepatitis C virus infection and HCV genotypes among hemophiliacs in the State of Bahia, Northeastern Brazil: analysis of serological and virological parameters
Paraná, Raymundo
Hepatitis C virus
Hemophilia
Prevalence
Genotype
Bahia
title_short Prevalence of hepatitis C virus infection and HCV genotypes among hemophiliacs in the State of Bahia, Northeastern Brazil: analysis of serological and virological parameters
title_full Prevalence of hepatitis C virus infection and HCV genotypes among hemophiliacs in the State of Bahia, Northeastern Brazil: analysis of serological and virological parameters
title_fullStr Prevalence of hepatitis C virus infection and HCV genotypes among hemophiliacs in the State of Bahia, Northeastern Brazil: analysis of serological and virological parameters
title_full_unstemmed Prevalence of hepatitis C virus infection and HCV genotypes among hemophiliacs in the State of Bahia, Northeastern Brazil: analysis of serological and virological parameters
title_sort Prevalence of hepatitis C virus infection and HCV genotypes among hemophiliacs in the State of Bahia, Northeastern Brazil: analysis of serological and virological parameters
author Paraná, Raymundo
author_facet Paraná, Raymundo
Reis, Galvão dos
Silva, Luciano Kalabric
Silva, Maria Betânia Souza da
Lopes, Gisele Barreto
Rodart, Itatiana Ferreira
Costa, Fernando Quadros
Santana, Nelma Pereira de
Santana, Aurelino
author_role author
author2 Reis, Galvão dos
Silva, Luciano Kalabric
Silva, Maria Betânia Souza da
Lopes, Gisele Barreto
Rodart, Itatiana Ferreira
Costa, Fernando Quadros
Santana, Nelma Pereira de
Santana, Aurelino
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Paraná, Raymundo
Reis, Galvão dos
Silva, Luciano Kalabric
Silva, Maria Betânia Souza da
Lopes, Gisele Barreto
Rodart, Itatiana Ferreira
Costa, Fernando Quadros
Santana, Nelma Pereira de
Santana, Aurelino
Paraná, Raymundo
Reis, Galvão dos
Silva, Luciano Kalabric
Silva, Maria Betânia Souza da
Lopes, Gisele Barreto
Rodart, Itatiana Ferreira
Costa, Fernando Quadros
Santana, Nelma Pereira de
Santana, Aurelino
dc.subject.por.fl_str_mv Hepatitis C virus
Hemophilia
Prevalence
Genotype
Bahia
topic Hepatitis C virus
Hemophilia
Prevalence
Genotype
Bahia
description p.496-502
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2013-11-01T19:13:53Z
dc.date.available.fl_str_mv 2013-11-01T19:13:53Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/13490
dc.identifier.issn.none.fl_str_mv 0037-8682
dc.identifier.number.pt_BR.fl_str_mv v.38 n. 6
identifier_str_mv 0037-8682
v.38 n. 6
url http://repositorio.ufba.br/ri/handle/ri/13490
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.country.fl_str_mv Brasil
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1590/S0037-86822005000600010
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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