Computational Modelling and Simulation of Fluid Structure Interaction in Aortic Aneurysms

Bibliographic Details
Main Author: Mourato, André
Publication Date: 2022
Other Authors: Valente, Rodrigo, Xavier, José, Brito, Moisés, Avril, Stéphane, de Sá, José César, Tomás, António, Fragata, José
Format: Other
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/145843
Summary: R. Valente PhD grant 2022.12223.BD. Publisher Copyright: © 2022 by the authors.
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spelling Computational Modelling and Simulation of Fluid Structure Interaction in Aortic AneurysmsA Systematic Review and Discussion of the Clinical Potentialadvanced in silico modelsaortic aneurysmsblood vessel interactionfluid–structure interactionMaterials Science(all)InstrumentationEngineering(all)Process Chemistry and TechnologyComputer Science ApplicationsFluid Flow and Transfer ProcessesSDG 3 - Good Health and Well-beingR. Valente PhD grant 2022.12223.BD. Publisher Copyright: © 2022 by the authors.Aortic aneurysm is a cardiovascular disease related to the alteration of the aortic tissue. It is an important cause of death in developed countries, especially for older patients. The diagnosis and treatment of such pathology is performed according to guidelines, which suggest surgical or interventional (stenting) procedures for aneurysms with a maximum diameter above a critical threshold. Although conservative, this clinical approach is also not able to predict the risk of acute complications for every patient. In the last decade, there has been growing interest towards the development of advanced in silico aortic models, which may assist in clinical diagnosis, surgical procedure planning or the design and validation of medical devices. This paper details a comprehensive review of computational modelling and simulations of blood vessel interaction in aortic aneurysms and dissection, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). In particular, the following questions are addressed: “What mathematical models were applied to simulate the biomechanical behaviour of healthy and diseased aortas?” and “Why are these models not clinically implemented?”. Contemporary evidence proves that computational models are able to provide clinicians with additional, otherwise unavailable in vivo data and potentially identify patients who may benefit from earlier treatment. Notwithstanding the above, these tools are still not widely implemented, primarily due to low accuracy, an extensive reporting time and lack of numerical validation.DEMI - Departamento de Engenharia Mecânica e IndustrialUNIDEMI - Unidade de Investigação e Desenvolvimento em Engenharia Mecânica e IndustrialNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNMourato, AndréValente, RodrigoXavier, JoséBrito, MoisésAvril, Stéphanede Sá, José CésarTomás, AntónioFragata, José2022-11-28T22:13:42Z2022-08-112022-08-11T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/other38application/pdfhttp://hdl.handle.net/10362/145843eng2076-3417PURE: 46600136https://doi.org/10.3390/app12168049info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T18:06:58Zoai:run.unl.pt:10362/145843Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:37:23.452001Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Computational Modelling and Simulation of Fluid Structure Interaction in Aortic Aneurysms
A Systematic Review and Discussion of the Clinical Potential
title Computational Modelling and Simulation of Fluid Structure Interaction in Aortic Aneurysms
spellingShingle Computational Modelling and Simulation of Fluid Structure Interaction in Aortic Aneurysms
Mourato, André
advanced in silico models
aortic aneurysms
blood vessel interaction
fluid–structure interaction
Materials Science(all)
Instrumentation
Engineering(all)
Process Chemistry and Technology
Computer Science Applications
Fluid Flow and Transfer Processes
SDG 3 - Good Health and Well-being
title_short Computational Modelling and Simulation of Fluid Structure Interaction in Aortic Aneurysms
title_full Computational Modelling and Simulation of Fluid Structure Interaction in Aortic Aneurysms
title_fullStr Computational Modelling and Simulation of Fluid Structure Interaction in Aortic Aneurysms
title_full_unstemmed Computational Modelling and Simulation of Fluid Structure Interaction in Aortic Aneurysms
title_sort Computational Modelling and Simulation of Fluid Structure Interaction in Aortic Aneurysms
author Mourato, André
author_facet Mourato, André
Valente, Rodrigo
Xavier, José
Brito, Moisés
Avril, Stéphane
de Sá, José César
Tomás, António
Fragata, José
author_role author
author2 Valente, Rodrigo
Xavier, José
Brito, Moisés
Avril, Stéphane
de Sá, José César
Tomás, António
Fragata, José
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv DEMI - Departamento de Engenharia Mecânica e Industrial
UNIDEMI - Unidade de Investigação e Desenvolvimento em Engenharia Mecânica e Industrial
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Mourato, André
Valente, Rodrigo
Xavier, José
Brito, Moisés
Avril, Stéphane
de Sá, José César
Tomás, António
Fragata, José
dc.subject.por.fl_str_mv advanced in silico models
aortic aneurysms
blood vessel interaction
fluid–structure interaction
Materials Science(all)
Instrumentation
Engineering(all)
Process Chemistry and Technology
Computer Science Applications
Fluid Flow and Transfer Processes
SDG 3 - Good Health and Well-being
topic advanced in silico models
aortic aneurysms
blood vessel interaction
fluid–structure interaction
Materials Science(all)
Instrumentation
Engineering(all)
Process Chemistry and Technology
Computer Science Applications
Fluid Flow and Transfer Processes
SDG 3 - Good Health and Well-being
description R. Valente PhD grant 2022.12223.BD. Publisher Copyright: © 2022 by the authors.
publishDate 2022
dc.date.none.fl_str_mv 2022-11-28T22:13:42Z
2022-08-11
2022-08-11T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/other
format other
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/145843
url http://hdl.handle.net/10362/145843
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2076-3417
PURE: 46600136
https://doi.org/10.3390/app12168049
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 38
application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833596842443538432

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