FAAH rs324420 Polymorphism Is Associated with Performance in Elite Rink-Hockey Players

Bibliographic Details
Main Author: Silva, Hugo Henrique
Publication Date: 2022
Other Authors: Tavares, Valéria, Silva, Maria Raquel G., Neto, Beatriz Vieira, Cerqueira, Fátima, Medeiros, Rui
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/143583
Summary: Funding Information: This research was supported by research found ICBAS-PDBiomedical Sciences-200203100 and Portuguese League Against Cancer—Northern Branch (LPCC-NRN).
id RCAP_f3d7b543e25497dea6143d7c9b33c58a
oai_identifier_str oai:run.unl.pt:10362/143583
network_acronym_str RCAP
network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository_id_str https://opendoar.ac.uk/repository/7160
spelling FAAH rs324420 Polymorphism Is Associated with Performance in Elite Rink-Hockey Playerselite athletegeneperformancepolymorphismrink-hockeysportsuccessBiochemistry, Genetics and Molecular Biology(all)Immunology and Microbiology(all)Agricultural and Biological Sciences(all)Funding Information: This research was supported by research found ICBAS-PDBiomedical Sciences-200203100 and Portuguese League Against Cancer—Northern Branch (LPCC-NRN).Genetic factors are among the major contributors to athletic performance. Although more than 150 genetic variants have been correlated with elite athlete status, genetic foundations of competition-facilitating behavior influencing elite performances are still scarce. This is the first study designed to examine the distribution of genetic determinants in the athletic performance of elite rink-hockey players. A total of 116 of the world’s top best rink-hockey players (28.2 ± 8.7 years old; more than 50% are cumulatively from the best four world teams and the best five Portuguese teams), who participated at the elite level in the National Rink-Hockey Championship in Portugal, were evaluated in anthropometric indicators/measurements, training conditions, sport experience and sport injuries history. Seven genetic polymorphisms were analyzed. Polymorphism genotyping was performed using the TaqMan® Allelic Discrimination Methodology. Rink-hockey players demonstrated significantly different characteristics according to sex, namely anthropometrics, training habits, sports injuries and genetic variants, such as Vitamin D Receptor (VDR) rs731236 (p < 0.05). The Fatty Acid Amide Hydrolase (FAAH) rs324420 A allele was significantly associated with improved athletic performance (AA/AC vs. CC, OR = 2.80; 95% Cl, 1.23–6.35; p = 0.014; p = 0.008 after Bootstrap) and confirmed as an independent predictor among elite rink-hockey players (adjusted OR = 2.88; 95% Cl, 1.06–7.80; p = 0.038). Our results open an interesting link from FAAH-related biology to athletic performance.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNSilva, Hugo HenriqueTavares, ValériaSilva, Maria Raquel G.Neto, Beatriz VieiraCerqueira, FátimaMedeiros, Rui2022-09-07T23:15:05Z2022-072022-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/143583engPURE: 46238640https://doi.org/10.3390/biology11071076info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T18:04:57Zoai:run.unl.pt:10362/143583Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:35:37.635775Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv FAAH rs324420 Polymorphism Is Associated with Performance in Elite Rink-Hockey Players
title FAAH rs324420 Polymorphism Is Associated with Performance in Elite Rink-Hockey Players
spellingShingle FAAH rs324420 Polymorphism Is Associated with Performance in Elite Rink-Hockey Players
Silva, Hugo Henrique
elite athlete
gene
performance
polymorphism
rink-hockey
sport
success
Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)
Agricultural and Biological Sciences(all)
title_short FAAH rs324420 Polymorphism Is Associated with Performance in Elite Rink-Hockey Players
title_full FAAH rs324420 Polymorphism Is Associated with Performance in Elite Rink-Hockey Players
title_fullStr FAAH rs324420 Polymorphism Is Associated with Performance in Elite Rink-Hockey Players
title_full_unstemmed FAAH rs324420 Polymorphism Is Associated with Performance in Elite Rink-Hockey Players
title_sort FAAH rs324420 Polymorphism Is Associated with Performance in Elite Rink-Hockey Players
author Silva, Hugo Henrique
author_facet Silva, Hugo Henrique
Tavares, Valéria
Silva, Maria Raquel G.
Neto, Beatriz Vieira
Cerqueira, Fátima
Medeiros, Rui
author_role author
author2 Tavares, Valéria
Silva, Maria Raquel G.
Neto, Beatriz Vieira
Cerqueira, Fátima
Medeiros, Rui
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Silva, Hugo Henrique
Tavares, Valéria
Silva, Maria Raquel G.
Neto, Beatriz Vieira
Cerqueira, Fátima
Medeiros, Rui
dc.subject.por.fl_str_mv elite athlete
gene
performance
polymorphism
rink-hockey
sport
success
Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)
Agricultural and Biological Sciences(all)
topic elite athlete
gene
performance
polymorphism
rink-hockey
sport
success
Biochemistry, Genetics and Molecular Biology(all)
Immunology and Microbiology(all)
Agricultural and Biological Sciences(all)
description Funding Information: This research was supported by research found ICBAS-PDBiomedical Sciences-200203100 and Portuguese League Against Cancer—Northern Branch (LPCC-NRN).
publishDate 2022
dc.date.none.fl_str_mv 2022-09-07T23:15:05Z
2022-07
2022-07-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/143583
url http://hdl.handle.net/10362/143583
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv PURE: 46238640
https://doi.org/10.3390/biology11071076
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833596817556635648

Similar Items