Cross-cutting computational strategies to genome-scale modelling

Detalhes bibliográficos
Autor(a) principal: Lourenço, Anália
Data de Publicação: 2010
Outros Autores: Carneiro, S., Rocha, I., Ferreira, Eugénio C.
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: https://hdl.handle.net/1822/23826
Resumo: Book of abstracts of the Meeting of the Institute for Biotechnology and Bioengineering, 2, Braga, Portugal, 2010
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spelling Cross-cutting computational strategies to genome-scale modellingBook of abstracts of the Meeting of the Institute for Biotechnology and Bioengineering, 2, Braga, Portugal, 2010Hereby, the aim is to present some of our research efforts towards the reconstruction of genome-scale models. Namely, we focus on the development of cross-cutting computational strategies for the integration and validation of heterogeneous data in support to traditional manual curation and, describe application scenarios on the model organism E. coli. We address the systematic comparison of database contents and the harvest and extraction of contents from scientific literature. Aiming to help researchers assess the gains and losses to be accounted for in biological repositories and thus, choose the most content-bearing repositories for each particular integration problem/domain, we have implemented a Webalike report tool [1]. This tool analyses the contents of well-known repositories under userspecified integration scenarios considering the coverage of main biological entities (genes, proteins and compounds) and the evaluation of standard nomenclatures, common names and repository cross-links as elements of integration. Also, acknowledging that most biological data still lays on scientific literature and requires extensive and time-consuming manual curation, we have been developing literature screening and processing tools [2]. The goal is to systematise the search of relevant literature based on user-specified keywords and the extraction of relevant information by applying statistical approaches that exploit simple pattern matching, machine learning and ontological enrichment. Considering the wide scope of current applications that can benefit from the analysis of large amounts of data, all our tools are publicly available through our group’s Web pages (http://biopseg.deb.uminho.pt).Universidade do Minho. Centro de Engenharia Biológica (CEB)Departamento de Engenharia Biológica da Universidade do MinhoUniversidade do MinhoLourenço, AnáliaCarneiro, S.Rocha, I.Ferreira, Eugénio C.2010-102010-10-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/1822/23826eng978-972-97810-6-3info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-11T04:22:06Zoai:repositorium.sdum.uminho.pt:1822/23826Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T14:46:19.304218Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Cross-cutting computational strategies to genome-scale modelling
title Cross-cutting computational strategies to genome-scale modelling
spellingShingle Cross-cutting computational strategies to genome-scale modelling
Lourenço, Anália
title_short Cross-cutting computational strategies to genome-scale modelling
title_full Cross-cutting computational strategies to genome-scale modelling
title_fullStr Cross-cutting computational strategies to genome-scale modelling
title_full_unstemmed Cross-cutting computational strategies to genome-scale modelling
title_sort Cross-cutting computational strategies to genome-scale modelling
author Lourenço, Anália
author_facet Lourenço, Anália
Carneiro, S.
Rocha, I.
Ferreira, Eugénio C.
author_role author
author2 Carneiro, S.
Rocha, I.
Ferreira, Eugénio C.
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Lourenço, Anália
Carneiro, S.
Rocha, I.
Ferreira, Eugénio C.
description Book of abstracts of the Meeting of the Institute for Biotechnology and Bioengineering, 2, Braga, Portugal, 2010
publishDate 2010
dc.date.none.fl_str_mv 2010-10
2010-10-01T00:00:00Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/23826
url https://hdl.handle.net/1822/23826
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 978-972-97810-6-3
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade do Minho. Centro de Engenharia Biológica (CEB)
Departamento de Engenharia Biológica da Universidade do Minho
publisher.none.fl_str_mv Universidade do Minho. Centro de Engenharia Biológica (CEB)
Departamento de Engenharia Biológica da Universidade do Minho
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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