Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair

• Main Author: Souto, Eliana B.
• Publication Date: 2021
• Other Authors: Yoshida, Cristiana M. P., Leonardi, Gislaine R., Cano, Amanda, Sanchez-Lopez, Elena, Zielińska, Aleksandra, Viseras, César, Severino, Patrícia, Silva, Classius F. da, Barbosa, Raquel de M.
• Format: Article
• Language: eng
• Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
• Download full: https://hdl.handle.net/10316/105342; https://doi.org/10.3390/pharmaceutics13081199
• topic: biopolymers; lipid-polymeric films; lipids; skin repair

The use of lipids in the composition of polymeric-based films for topical administration of bioactive ingredients is a recent research topic; while few products are commercially available, films containing lipids represent a strategic area for the development of new products. Some lipids are usually used in polymeric-based film formulations due to their plasticizing action, with a view to improving the mechanical properties of these films. On the other hand, many lipids have healing, antimicrobial, anti-inflammatory, anti-aging properties, among others, that make them even more interesting for application in the medical-pharmaceutical field. This manuscript discusses the production methods of these films both on a laboratory and at industrial scales, the properties of the developed biopolymers, and their advantages for the development of dermatologic and cosmetic products.