Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity Federation

Bibliographic Details
Main Author: Lopez-Jimenez, Francisco
Publication Date: 2022
Other Authors: Almahmeed, Wael, Bays, Harold, Cuevas, Ada, Di Angelantonio, Emanuele, le Roux, Carel W., Sattar, Naveed, Sun, Marie Chan, Wittert, Gary, Pinto, Fausto J., Wilding, John P. H.
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10451/55466
Summary: © The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
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spelling Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity FederationAdiposityCardiometabolic complicationsCardiovascular diseaseCardiovascular riskOverweightObesity© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.comThe ongoing obesity epidemic represents a global public health crisis that contributes to poor health outcomes, reduced quality of life, and >2.8 million deaths each year. Obesity is relapsing, progressive, and heterogeneous. It is considered a chronic disease by the World Obesity Federation (WOF) and a chronic condition by the World Heart Federation (WHF). People living with overweight/obesity are at greater risk for cardiovascular (CV) morbidity and mortality. Increased adiposity (body fat), particularly visceral/abdominal fat, is linked to CV risk and CV disease (CVD) via multiple direct and indirect pathophysiological mechanisms. The development of CVD is driven, in part, by obesity-related metabolic, endocrinologic, immunologic, structural, humoral, haemodynamic, and functional alterations. The complex multifaceted nature of these mechanisms can be challenging to understand and address in clinical practice. People living with obesity and CVD often have concurrent chronic physical or psychological disorders (multimorbidity) requiring multidisciplinary care pathways and polypharmacy. Evidence indicates that intentional weight loss (particularly when substantial) lowers CVD risk among people with overweight/obesity. Long-term weight loss and maintenance require ongoing commitment from both the individual and those responsible for their care. This position paper, developed by the WOF and the WHF, aims to improve understanding of the direct and indirect links between overweight/obesity and CVD, the key controversies in this area and evidence relating to cardiometabolic outcomes with available weight management options. Finally, an action plan for clinicians provides recommendations to help in identifying and addressing the risks of obesity-related CVD (recognizing resource and support variances between countries).Oxford University PressRepositório da Universidade de LisboaLopez-Jimenez, FranciscoAlmahmeed, WaelBays, HaroldCuevas, AdaDi Angelantonio, Emanuelele Roux, Carel W.Sattar, NaveedSun, Marie ChanWittert, GaryPinto, Fausto J.Wilding, John P. H.2022-12-20T15:41:06Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/55466engEur J Prev Cardiol 2022 Dec 7;29(17):2218-22372047-487310.1093/eurjpc/zwac1872047-4881info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T14:51:46Zoai:repositorio.ulisboa.pt:10451/55466Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T03:27:01.912437Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity Federation
title Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity Federation
spellingShingle Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity Federation
Lopez-Jimenez, Francisco
Adiposity
Cardiometabolic complications
Cardiovascular disease
Cardiovascular risk
Overweight
Obesity
title_short Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity Federation
title_full Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity Federation
title_fullStr Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity Federation
title_full_unstemmed Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity Federation
title_sort Obesity and cardiovascular disease: mechanistic insights and management strategies. A joint position paper by the World Heart Federation and World Obesity Federation
author Lopez-Jimenez, Francisco
author_facet Lopez-Jimenez, Francisco
Almahmeed, Wael
Bays, Harold
Cuevas, Ada
Di Angelantonio, Emanuele
le Roux, Carel W.
Sattar, Naveed
Sun, Marie Chan
Wittert, Gary
Pinto, Fausto J.
Wilding, John P. H.
author_role author
author2 Almahmeed, Wael
Bays, Harold
Cuevas, Ada
Di Angelantonio, Emanuele
le Roux, Carel W.
Sattar, Naveed
Sun, Marie Chan
Wittert, Gary
Pinto, Fausto J.
Wilding, John P. H.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Lopez-Jimenez, Francisco
Almahmeed, Wael
Bays, Harold
Cuevas, Ada
Di Angelantonio, Emanuele
le Roux, Carel W.
Sattar, Naveed
Sun, Marie Chan
Wittert, Gary
Pinto, Fausto J.
Wilding, John P. H.
dc.subject.por.fl_str_mv Adiposity
Cardiometabolic complications
Cardiovascular disease
Cardiovascular risk
Overweight
Obesity
topic Adiposity
Cardiometabolic complications
Cardiovascular disease
Cardiovascular risk
Overweight
Obesity
description © The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
publishDate 2022
dc.date.none.fl_str_mv 2022-12-20T15:41:06Z
2022
2022-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/55466
url http://hdl.handle.net/10451/55466
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Eur J Prev Cardiol 2022 Dec 7;29(17):2218-2237
2047-4873
10.1093/eurjpc/zwac187
2047-4881
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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