Diastolic Dysfunction in Hypertension

Detalhes bibliográficos
Autor(a) principal: Nazário Leão, R
Data de Publicação: 2017
Outros Autores: Marques da Silva, P
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: http://hdl.handle.net/10400.17/4798
Resumo: Hypertension and coronary heart disease, often coexisting, are the most common risk factors for heart failure. The progression of hypertensive heart disease involves myocardial fibrosis and alterations in the left ventricular geometry that precede the functional change, initially asymptomatic. The left ventricular diastolic dysfunction is part of this continuum being defined by the presence of left ventricular diastolic dysfunction without signs or symptoms of heart failure or poor left ventricular systolic function. It is highly prevalent in hypertensive patients and is associated with increased cardiovascular morbidity and mortality. Despite its growing importance in clinical practice it remains poorly understood. This review aims to present the epidemiological fundamentals and the latest developments in the pathophysiology, diagnosis and treatment of left ventricular diastolic dysfunction.
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spelling Diastolic Dysfunction in HypertensionHSJ MEDHSM MEDHumansDiastolic DysfunctionHypertensionHypertensive Heart DiseaseLeft Ventricular GeometryHeart Failure with Preserved Ejection FractionHypertension and coronary heart disease, often coexisting, are the most common risk factors for heart failure. The progression of hypertensive heart disease involves myocardial fibrosis and alterations in the left ventricular geometry that precede the functional change, initially asymptomatic. The left ventricular diastolic dysfunction is part of this continuum being defined by the presence of left ventricular diastolic dysfunction without signs or symptoms of heart failure or poor left ventricular systolic function. It is highly prevalent in hypertensive patients and is associated with increased cardiovascular morbidity and mortality. Despite its growing importance in clinical practice it remains poorly understood. This review aims to present the epidemiological fundamentals and the latest developments in the pathophysiology, diagnosis and treatment of left ventricular diastolic dysfunction.ElsevierRepositório da Unidade Local de Saúde São JoséNazário Leão, RMarques da Silva, P2024-02-08T14:42:59Z2017-072017-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/4798eng10.1016/j.hipert.2017.01.001info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-06T16:48:30Zoai:repositorio.chlc.pt:10400.17/4798Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T00:19:47.697404Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Diastolic Dysfunction in Hypertension
title Diastolic Dysfunction in Hypertension
spellingShingle Diastolic Dysfunction in Hypertension
Nazário Leão, R
HSJ MED
HSM MED
Humans
Diastolic Dysfunction
Hypertension
Hypertensive Heart Disease
Left Ventricular Geometry
Heart Failure with Preserved Ejection Fraction
title_short Diastolic Dysfunction in Hypertension
title_full Diastolic Dysfunction in Hypertension
title_fullStr Diastolic Dysfunction in Hypertension
title_full_unstemmed Diastolic Dysfunction in Hypertension
title_sort Diastolic Dysfunction in Hypertension
author Nazário Leão, R
author_facet Nazário Leão, R
Marques da Silva, P
author_role author
author2 Marques da Silva, P
author2_role author
dc.contributor.none.fl_str_mv Repositório da Unidade Local de Saúde São José
dc.contributor.author.fl_str_mv Nazário Leão, R
Marques da Silva, P
dc.subject.por.fl_str_mv HSJ MED
HSM MED
Humans
Diastolic Dysfunction
Hypertension
Hypertensive Heart Disease
Left Ventricular Geometry
Heart Failure with Preserved Ejection Fraction
topic HSJ MED
HSM MED
Humans
Diastolic Dysfunction
Hypertension
Hypertensive Heart Disease
Left Ventricular Geometry
Heart Failure with Preserved Ejection Fraction
description Hypertension and coronary heart disease, often coexisting, are the most common risk factors for heart failure. The progression of hypertensive heart disease involves myocardial fibrosis and alterations in the left ventricular geometry that precede the functional change, initially asymptomatic. The left ventricular diastolic dysfunction is part of this continuum being defined by the presence of left ventricular diastolic dysfunction without signs or symptoms of heart failure or poor left ventricular systolic function. It is highly prevalent in hypertensive patients and is associated with increased cardiovascular morbidity and mortality. Despite its growing importance in clinical practice it remains poorly understood. This review aims to present the epidemiological fundamentals and the latest developments in the pathophysiology, diagnosis and treatment of left ventricular diastolic dysfunction.
publishDate 2017
dc.date.none.fl_str_mv 2017-07
2017-07-01T00:00:00Z
2024-02-08T14:42:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/4798
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.hipert.2017.01.001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Elsevier
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collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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