Fluorescence studies of potential antitumoral 6-heteroarylthieno[3,2-b]pyridines in solution and in nanoliposomes

Bibliographic Details
Main Author: Carvalho, M. Solange D.
Publication Date: 2012
Other Authors: Castanheira, Elisabete M. S., Oliveira, Andreia D. S., Calhelha, Ricardo C., Queiroz, Maria João R. P.
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/1822/19952
Summary: Fluorescence properties of new potential antitumoral 6-heteroarylthieno[3,2-b]pyridines, recently synthesized, were studied in solution and in nanoliposomes of different compositions. The results indicate that these compounds can be transported in the hydrophobic region of the lipid bilayer. The liposomal formulation Egg-PC:Ch:DPPG (7:3:1) is the one with smaller size and lowest polydispersity.
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spelling Fluorescence studies of potential antitumoral 6-heteroarylthieno[3,2-b]pyridines in solution and in nanoliposomesAntitumoral compoundsFluorescenceThieno[3,2-b]pyridinesNanoliposomesFluorescence properties of new potential antitumoral 6-heteroarylthieno[3,2-b]pyridines, recently synthesized, were studied in solution and in nanoliposomes of different compositions. The results indicate that these compounds can be transported in the hydrophobic region of the lipid bilayer. The liposomal formulation Egg-PC:Ch:DPPG (7:3:1) is the one with smaller size and lowest polydispersity.CFUM - PEst-C/FIS/UI0607/2011 (F-COMP-01-0124-FEDER-022711)Fundação para a Ciência e a Tecnologia - SFRH/BD/47052/2008)CQ/UM - PEst-C/QUI/UI0686/2011 (FCOMP-01-0124-FEDER-022716), PTDC/QUI/81238/2006 (FCOMP-01-0124-FEDER-007467)FEDERUniversidade do MinhoCarvalho, M. Solange D.Castanheira, Elisabete M. S.Oliveira, Andreia D. S.Calhelha, Ricardo C.Queiroz, Maria João R. P.2012-072012-07-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/1822/19952enginfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-11T06:06:56Zoai:repositorium.sdum.uminho.pt:1822/19952Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T15:41:37.738822Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Fluorescence studies of potential antitumoral 6-heteroarylthieno[3,2-b]pyridines in solution and in nanoliposomes
title Fluorescence studies of potential antitumoral 6-heteroarylthieno[3,2-b]pyridines in solution and in nanoliposomes
spellingShingle Fluorescence studies of potential antitumoral 6-heteroarylthieno[3,2-b]pyridines in solution and in nanoliposomes
Carvalho, M. Solange D.
Antitumoral compounds
Fluorescence
Thieno[3,2-b]pyridines
Nanoliposomes
title_short Fluorescence studies of potential antitumoral 6-heteroarylthieno[3,2-b]pyridines in solution and in nanoliposomes
title_full Fluorescence studies of potential antitumoral 6-heteroarylthieno[3,2-b]pyridines in solution and in nanoliposomes
title_fullStr Fluorescence studies of potential antitumoral 6-heteroarylthieno[3,2-b]pyridines in solution and in nanoliposomes
title_full_unstemmed Fluorescence studies of potential antitumoral 6-heteroarylthieno[3,2-b]pyridines in solution and in nanoliposomes
title_sort Fluorescence studies of potential antitumoral 6-heteroarylthieno[3,2-b]pyridines in solution and in nanoliposomes
author Carvalho, M. Solange D.
author_facet Carvalho, M. Solange D.
Castanheira, Elisabete M. S.
Oliveira, Andreia D. S.
Calhelha, Ricardo C.
Queiroz, Maria João R. P.
author_role author
author2 Castanheira, Elisabete M. S.
Oliveira, Andreia D. S.
Calhelha, Ricardo C.
Queiroz, Maria João R. P.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Carvalho, M. Solange D.
Castanheira, Elisabete M. S.
Oliveira, Andreia D. S.
Calhelha, Ricardo C.
Queiroz, Maria João R. P.
dc.subject.por.fl_str_mv Antitumoral compounds
Fluorescence
Thieno[3,2-b]pyridines
Nanoliposomes
topic Antitumoral compounds
Fluorescence
Thieno[3,2-b]pyridines
Nanoliposomes
description Fluorescence properties of new potential antitumoral 6-heteroarylthieno[3,2-b]pyridines, recently synthesized, were studied in solution and in nanoliposomes of different compositions. The results indicate that these compounds can be transported in the hydrophobic region of the lipid bilayer. The liposomal formulation Egg-PC:Ch:DPPG (7:3:1) is the one with smaller size and lowest polydispersity.
publishDate 2012
dc.date.none.fl_str_mv 2012-07
2012-07-01T00:00:00Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/19952
url http://hdl.handle.net/1822/19952
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
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reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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