Digital pathology in the immunohistochemical evaluation of biomarkers in breast cancer

Detalhes bibliográficos
Autor(a) principal: Lopes, J.
Data de Publicação: 2021
Outros Autores: Silva, S., Monteiro, J., Pinto, I.M., Silva, Regina
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: http://hdl.handle.net/10400.22/25728
Resumo: Currently, the evaluation of biomarkers HER-2 and ER is critical for targeting therapy for breast cancer and is performed by experienced pathologists, which takes time and causes a certain interobserver variability. The use of histological slide scanners coupled with the application of software for immunoexpression quantification can be profitable in pathological laboratories routine. This study aims to compare the quantification of HER-2 and ER immunoexpression employing automatic algorithms, using as standard the evaluation performed by a pathologist.
id RCAP_c7cc6d829632db9b92aac9e48f8cff9c
oai_identifier_str oai:recipp.ipp.pt:10400.22/25728
network_acronym_str RCAP
network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository_id_str https://opendoar.ac.uk/repository/7160
spelling Digital pathology in the immunohistochemical evaluation of biomarkers in breast cancerBreast cancerBiomarkersDigital pathologyImmunoexpressionCurrently, the evaluation of biomarkers HER-2 and ER is critical for targeting therapy for breast cancer and is performed by experienced pathologists, which takes time and causes a certain interobserver variability. The use of histological slide scanners coupled with the application of software for immunoexpression quantification can be profitable in pathological laboratories routine. This study aims to compare the quantification of HER-2 and ER immunoexpression employing automatic algorithms, using as standard the evaluation performed by a pathologist.OXFORD AcademicREPOSITÓRIO P.PORTOLopes, J.Silva, S.Monteiro, J.Pinto, I.M.Silva, Regina2024-07-02T15:22:44Z2021-08-032021-08-03T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10400.22/25728eng1101-126210.1093/eurpub/ckab120.073info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-07T10:19:23Zoai:recipp.ipp.pt:10400.22/25728Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T00:48:24.318723Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Digital pathology in the immunohistochemical evaluation of biomarkers in breast cancer
title Digital pathology in the immunohistochemical evaluation of biomarkers in breast cancer
spellingShingle Digital pathology in the immunohistochemical evaluation of biomarkers in breast cancer
Lopes, J.
Breast cancer
Biomarkers
Digital pathology
Immunoexpression
title_short Digital pathology in the immunohistochemical evaluation of biomarkers in breast cancer
title_full Digital pathology in the immunohistochemical evaluation of biomarkers in breast cancer
title_fullStr Digital pathology in the immunohistochemical evaluation of biomarkers in breast cancer
title_full_unstemmed Digital pathology in the immunohistochemical evaluation of biomarkers in breast cancer
title_sort Digital pathology in the immunohistochemical evaluation of biomarkers in breast cancer
author Lopes, J.
author_facet Lopes, J.
Silva, S.
Monteiro, J.
Pinto, I.M.
Silva, Regina
author_role author
author2 Silva, S.
Monteiro, J.
Pinto, I.M.
Silva, Regina
author2_role author
author
author
author
dc.contributor.none.fl_str_mv REPOSITÓRIO P.PORTO
dc.contributor.author.fl_str_mv Lopes, J.
Silva, S.
Monteiro, J.
Pinto, I.M.
Silva, Regina
dc.subject.por.fl_str_mv Breast cancer
Biomarkers
Digital pathology
Immunoexpression
topic Breast cancer
Biomarkers
Digital pathology
Immunoexpression
description Currently, the evaluation of biomarkers HER-2 and ER is critical for targeting therapy for breast cancer and is performed by experienced pathologists, which takes time and causes a certain interobserver variability. The use of histological slide scanners coupled with the application of software for immunoexpression quantification can be profitable in pathological laboratories routine. This study aims to compare the quantification of HER-2 and ER immunoexpression employing automatic algorithms, using as standard the evaluation performed by a pathologist.
publishDate 2021
dc.date.none.fl_str_mv 2021-08-03
2021-08-03T00:00:00Z
2024-07-02T15:22:44Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/25728
url http://hdl.handle.net/10400.22/25728
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1101-1262
10.1093/eurpub/ckab120.073
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv OXFORD Academic
publisher.none.fl_str_mv OXFORD Academic
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833600703654789120

Registros relacionados