THE INFLUENCE OF NECK THROMBUS AND TYPE OF ENDOPROTHESIS USED IN THE DEVELOPMENT OF ACUTE RENAL INJURY AFTER EVAR

Bibliographic Details
Main Author: Antunes, Inês
Publication Date: 2018
Other Authors: Machado, Rui, Rego, Duarte, Ferreira, Vítor, Gonçalves, João, Teixeira, Gabriela, Veiga, Carlos, Mendes, Daniel, Pereira, Carlos, Almeida, Rui
Format: Article
Language: por
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://doi.org/10.48750/acv.126
Summary: Introdution: Aneurysm neck morphology, in particular the presence of thrombus, may limit EVAR. Objetives: Study whether the presence of neck thrombus and type of endoprothesis used (supra or infra-renal fixation) has impact on renal function of patients treated by EVAR at our institution. Material/Methods: Retrospective analysis of the database of AAA treated by EVAR at our institution between December/2001 and December/2013. For each patient we evaluated creatinine/clearance in pre and postoperative periods. Of patients with renal function worsening, we selected those who had acute kidney injury (AKI) according to modified RIFLE criteria, and studied the relationship between AKI and neck thrombus and type of endoprosthesis used. From the database of 241 patients, renal failure patients at the procedure and those in which we didn’t have preoperative and postoperative renal function analyzes were excluded. Regarding the study of the relationship between endoprosthesis used and renal function: 127 were treated with supra-renal fixation endoprostheses, 74 with infra-renal fixation endoprostheses and 27 were excluded (thoracic endoprostheses or missed information). Regarding neck thrombus, we obtained this data for 190 patients. Results: Regarding the presence of neck thrombus and renal function in postoperative period: of the 190 patients, 21 (11%) developed AKI and neck thrombus in > 25% and> 50% of neck circumference presented statistically significant relationship with the development of AKI (p = 0.045 and p = 0.010, respectively). Regarding the study of endoprostheses used, 14.2% of the patients treated with supra-renal fixation endoprostheses and 5.4% of those treated with infra-renal fixation developed AKI in postoperative period. However, this difference wasn’t statistically significant (p = 0.052).  Discussion/Conclusions: Of our experience, neck thrombus is related to the development of AKI in postoperative period. Patients treated with supra-renal fixation endoprostheses developed more AKI in the postoperative period, but this difference was not statistically significant.
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spelling THE INFLUENCE OF NECK THROMBUS AND TYPE OF ENDOPROTHESIS USED IN THE DEVELOPMENT OF ACUTE RENAL INJURY AFTER EVARINFLUÊNCIA DO TROMBO DO COLO ANEURISMÁTICO E DO TIPO DE ENDOPRÓTESE UTILIZADA NO DESENVOLVIMENTO DE LESÃO RENAL AGUDA APÓS EVARAortic aneurysmEVARThrombusAcute kidney injuryAneurisma da AortaEVARTromboLesão renal agudaIntrodution: Aneurysm neck morphology, in particular the presence of thrombus, may limit EVAR. Objetives: Study whether the presence of neck thrombus and type of endoprothesis used (supra or infra-renal fixation) has impact on renal function of patients treated by EVAR at our institution. Material/Methods: Retrospective analysis of the database of AAA treated by EVAR at our institution between December/2001 and December/2013. For each patient we evaluated creatinine/clearance in pre and postoperative periods. Of patients with renal function worsening, we selected those who had acute kidney injury (AKI) according to modified RIFLE criteria, and studied the relationship between AKI and neck thrombus and type of endoprosthesis used. From the database of 241 patients, renal failure patients at the procedure and those in which we didn’t have preoperative and postoperative renal function analyzes were excluded. Regarding the study of the relationship between endoprosthesis used and renal function: 127 were treated with supra-renal fixation endoprostheses, 74 with infra-renal fixation endoprostheses and 27 were excluded (thoracic endoprostheses or missed information). Regarding neck thrombus, we obtained this data for 190 patients. Results: Regarding the presence of neck thrombus and renal function in postoperative period: of the 190 patients, 21 (11%) developed AKI and neck thrombus in > 25% and> 50% of neck circumference presented statistically significant relationship with the development of AKI (p = 0.045 and p = 0.010, respectively). Regarding the study of endoprostheses used, 14.2% of the patients treated with supra-renal fixation endoprostheses and 5.4% of those treated with infra-renal fixation developed AKI in postoperative period. However, this difference wasn’t statistically significant (p = 0.052).  Discussion/Conclusions: Of our experience, neck thrombus is related to the development of AKI in postoperative period. Patients treated with supra-renal fixation endoprostheses developed more AKI in the postoperative period, but this difference was not statistically significant.Introdução: As características do colo aneurismático, em particular a presença de trombo, podem limitar o tratamento por EVAR. Objetivos: Estudar se a presença de trombo no colo aneurismático e o tipo de endoprótese utilizada (fixação supra ou infra-renal) têm impacto na função renal dos doentes tratados por EVAR na nossa instituição. Materiais/Métodos: Análise retrospectiva da base de dados de doentes com AAA tratados por EVAR na nossa instituição entre dezembro/2001 e dezembro/2013. Para cada doente avaliamos o valor de creatinina e clearence nos pré e pós-operatório. Dos doentes com agravamento da função renal, selecionamos aqueles que tiveram lesão renal aguda (LRA) pelos critérios de RIFLE modificados, e estudamos a relação entre LRA e trombo do colo aneurismático e tipo de endoprótese utilizado. Da base de dados de 241 doentes foram excluídos os doentes IRC em hemodiálise à data do procedimento e aqueles em que não dispúnhamos de análises com função renal no pré e pós-operatório. Relativamente ao estudo da relação endoprótese utilizada e função renal: 127 foram tratados com endopróteses de fixação supra-renal, 74 com endoproteses de fixação infra-renal e 27 foram excluídos da análise por terem sido tratados com endopróteses torácicas ou não dispormos dessa informação. Relativamente ao estudo do trombo do colo aneurismático, conseguimos esse dado para 190 doentes. Resultados: relativamente ao impacto do trombo do colo aneurismático na função renal verificamos que dos 190 doentes estudados, 21 (11%) desenvolveram LRA no pós-operatório e a presença de trombo no colo em >25% e >50% da circunferência do colo, apresentou relação estatisticamente significativa com o desenvolvimento de LRA (p=0,045 e p=0,010, respetivamente). Relativamente ao estudo das endopróteses utilizadas, 14.2% dos doentes tratados com endopróteses de fixação supra-renal e 5.4% dos tratados com endopróteses de fixação infra-renal desenvolveram LRA no pos-operatório, no entanto esta diferença não se mostrou estatisticamente significativa (p=0,052). Discussão/conclusões: Na nossa experiência a presença de trombo do colo aneurismático teve  relação com o desenvolvimento de LRA no pós-operatório imediato mas não parece ter impacto na função renal aos 6 e 12 meses. Os doentes tratados com endopróteses de fixação supra-renal desenvolveram mais LRA no pós-operatório mas esta diferença não se mostrou estatisticamente significativa.Sociedade Portuguesa de Angiologia e Cirurgia Vascular2018-12-02T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.48750/acv.126oai:ojs.acvjournal.com:article/126Angiologia e Cirurgia Vascular; Vol. 14 No. 1 (2018): March; 13-18Angiologia e Cirurgia Vascular; Vol. 14 N.º 1 (2018): Março; 13-182183-00961646-706Xreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPporhttp://acvjournal.com/index.php/acv/article/view/126https://doi.org/10.48750/acv.126http://acvjournal.com/index.php/acv/article/view/126/77Copyright (c) 2018 Angiologia e Cirurgia Vascularinfo:eu-repo/semantics/openAccessAntunes, InêsMachado, RuiRego, DuarteFerreira, VítorGonçalves, JoãoTeixeira, GabrielaVeiga, CarlosMendes, DanielPereira, CarlosAlmeida, Rui2022-05-23T15:10:02Zoai:ojs.acvjournal.com:article/126Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T10:00:06.509374Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv THE INFLUENCE OF NECK THROMBUS AND TYPE OF ENDOPROTHESIS USED IN THE DEVELOPMENT OF ACUTE RENAL INJURY AFTER EVAR
INFLUÊNCIA DO TROMBO DO COLO ANEURISMÁTICO E DO TIPO DE ENDOPRÓTESE UTILIZADA NO DESENVOLVIMENTO DE LESÃO RENAL AGUDA APÓS EVAR
title THE INFLUENCE OF NECK THROMBUS AND TYPE OF ENDOPROTHESIS USED IN THE DEVELOPMENT OF ACUTE RENAL INJURY AFTER EVAR
spellingShingle THE INFLUENCE OF NECK THROMBUS AND TYPE OF ENDOPROTHESIS USED IN THE DEVELOPMENT OF ACUTE RENAL INJURY AFTER EVAR
Antunes, Inês
Aortic aneurysm
EVAR
Thrombus
Acute kidney injury
Aneurisma da Aorta
EVAR
Trombo
Lesão renal aguda
title_short THE INFLUENCE OF NECK THROMBUS AND TYPE OF ENDOPROTHESIS USED IN THE DEVELOPMENT OF ACUTE RENAL INJURY AFTER EVAR
title_full THE INFLUENCE OF NECK THROMBUS AND TYPE OF ENDOPROTHESIS USED IN THE DEVELOPMENT OF ACUTE RENAL INJURY AFTER EVAR
title_fullStr THE INFLUENCE OF NECK THROMBUS AND TYPE OF ENDOPROTHESIS USED IN THE DEVELOPMENT OF ACUTE RENAL INJURY AFTER EVAR
title_full_unstemmed THE INFLUENCE OF NECK THROMBUS AND TYPE OF ENDOPROTHESIS USED IN THE DEVELOPMENT OF ACUTE RENAL INJURY AFTER EVAR
title_sort THE INFLUENCE OF NECK THROMBUS AND TYPE OF ENDOPROTHESIS USED IN THE DEVELOPMENT OF ACUTE RENAL INJURY AFTER EVAR
author Antunes, Inês
author_facet Antunes, Inês
Machado, Rui
Rego, Duarte
Ferreira, Vítor
Gonçalves, João
Teixeira, Gabriela
Veiga, Carlos
Mendes, Daniel
Pereira, Carlos
Almeida, Rui
author_role author
author2 Machado, Rui
Rego, Duarte
Ferreira, Vítor
Gonçalves, João
Teixeira, Gabriela
Veiga, Carlos
Mendes, Daniel
Pereira, Carlos
Almeida, Rui
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Antunes, Inês
Machado, Rui
Rego, Duarte
Ferreira, Vítor
Gonçalves, João
Teixeira, Gabriela
Veiga, Carlos
Mendes, Daniel
Pereira, Carlos
Almeida, Rui
dc.subject.por.fl_str_mv Aortic aneurysm
EVAR
Thrombus
Acute kidney injury
Aneurisma da Aorta
EVAR
Trombo
Lesão renal aguda
topic Aortic aneurysm
EVAR
Thrombus
Acute kidney injury
Aneurisma da Aorta
EVAR
Trombo
Lesão renal aguda
description Introdution: Aneurysm neck morphology, in particular the presence of thrombus, may limit EVAR. Objetives: Study whether the presence of neck thrombus and type of endoprothesis used (supra or infra-renal fixation) has impact on renal function of patients treated by EVAR at our institution. Material/Methods: Retrospective analysis of the database of AAA treated by EVAR at our institution between December/2001 and December/2013. For each patient we evaluated creatinine/clearance in pre and postoperative periods. Of patients with renal function worsening, we selected those who had acute kidney injury (AKI) according to modified RIFLE criteria, and studied the relationship between AKI and neck thrombus and type of endoprosthesis used. From the database of 241 patients, renal failure patients at the procedure and those in which we didn’t have preoperative and postoperative renal function analyzes were excluded. Regarding the study of the relationship between endoprosthesis used and renal function: 127 were treated with supra-renal fixation endoprostheses, 74 with infra-renal fixation endoprostheses and 27 were excluded (thoracic endoprostheses or missed information). Regarding neck thrombus, we obtained this data for 190 patients. Results: Regarding the presence of neck thrombus and renal function in postoperative period: of the 190 patients, 21 (11%) developed AKI and neck thrombus in > 25% and> 50% of neck circumference presented statistically significant relationship with the development of AKI (p = 0.045 and p = 0.010, respectively). Regarding the study of endoprostheses used, 14.2% of the patients treated with supra-renal fixation endoprostheses and 5.4% of those treated with infra-renal fixation developed AKI in postoperative period. However, this difference wasn’t statistically significant (p = 0.052).  Discussion/Conclusions: Of our experience, neck thrombus is related to the development of AKI in postoperative period. Patients treated with supra-renal fixation endoprostheses developed more AKI in the postoperative period, but this difference was not statistically significant.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-02T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.48750/acv.126
oai:ojs.acvjournal.com:article/126
url https://doi.org/10.48750/acv.126
identifier_str_mv oai:ojs.acvjournal.com:article/126
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv http://acvjournal.com/index.php/acv/article/view/126
https://doi.org/10.48750/acv.126
http://acvjournal.com/index.php/acv/article/view/126/77
dc.rights.driver.fl_str_mv Copyright (c) 2018 Angiologia e Cirurgia Vascular
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Angiologia e Cirurgia Vascular
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
dc.source.none.fl_str_mv Angiologia e Cirurgia Vascular; Vol. 14 No. 1 (2018): March; 13-18
Angiologia e Cirurgia Vascular; Vol. 14 N.º 1 (2018): Março; 13-18
2183-0096
1646-706X
reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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