MERKEL CELL CARCINOMA – REPORT OF 7 CASES

Bibliographic Details
Main Author: Cabral, Rita
Publication Date: 2014
Other Authors: Brinca, Ana, Vieira, Ricardo, Mariano, Angelina, Tellechea, Óscar, Figueiredo, Américo
Format: Article
Language: por
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://doi.org/10.29021/spdv.71.2.166
Summary: Introduction: Merkel cell carcinoma is a rare, aggressive cutaneous neuroendocrine carcinoma that affects primarily elderly people. Patients present with a rapidly growing nodule, preferably located at the head, neck and limbs. Merkel cell carcinoma as a propensity for local recurrence and regional lymph node metastases and wide local excision is the initial consensual approach. The role of lymph node dissection, radiation therapy and chemotherapy is not yet clearly established. Material and Methods: The aim of this retrospective study was to evaluate Merkel cell carcinoma patients followed in our department between the years 2000 and 2009, regarding sex, age, race, clinical features, location, stage, associated malignancies, treatment and evolution.  Results: Our data are consistent with the literature, namely regarding age, associated lymphoproliferative disease and high local recurrence and mortality rates.
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spelling MERKEL CELL CARCINOMA – REPORT OF 7 CASESCARCINOMA DE CÉLULAS DE MERKEL – REVISÃO DE 7 CASOSCarcinomaMerkel cellSkin neoplasmsneuroendocrineCarcinoma de células de MerkelCarcinoma neuro-endócrinoIntroduction: Merkel cell carcinoma is a rare, aggressive cutaneous neuroendocrine carcinoma that affects primarily elderly people. Patients present with a rapidly growing nodule, preferably located at the head, neck and limbs. Merkel cell carcinoma as a propensity for local recurrence and regional lymph node metastases and wide local excision is the initial consensual approach. The role of lymph node dissection, radiation therapy and chemotherapy is not yet clearly established. Material and Methods: The aim of this retrospective study was to evaluate Merkel cell carcinoma patients followed in our department between the years 2000 and 2009, regarding sex, age, race, clinical features, location, stage, associated malignancies, treatment and evolution.  Results: Our data are consistent with the literature, namely regarding age, associated lymphoproliferative disease and high local recurrence and mortality rates.Introdução: O carcinoma de células de Merkel é um carcinoma neuro-endócrino raro, agressivo que se manifesta geralmente nos idosos. Apresenta-se geralmente como um nódulo de crescimento rápido localizado preferencialmente na cabeça, pescoço ou membros. Tem elevada taxa de recorrência loco-regional e à distância. A excisão cirúrgica radical é o tratamento consensual e o papel da linfadenectomia, da radioterapia e da quimioterapia ainda não está claramente estabelecido. Material e Métodos: O objectivo deste estudo retrospectivo passou por avaliar os doentes com carcinoma de células de Merkel observados no nosso serviço entre os anos de 2000 e 2009 relativamente ao sexo, idade, raça, clínica, localização do tumor, estadio, neoplasias associadas, tratamento e evolução.Resultados: Os dados desta casuística foram concordantes com os da literatura, nomeadamente quanto à idade, associação com processos linfoproliferativos B, elevadas taxas de recidiva loco-regional e de mortalidade.Sociedade Portuguesa de Dermatologia e Venereologia2014-06-24T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.71.2.166oai:ojs.revista.spdv.com.pt:article/166Journal of the Portuguese Society of Dermatology and Venereology; Vol 71 No 2 (2013): Abril-Junho; 171-176Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 71 n. 2 (2013): Abril-Junho; 171-1762182-24092182-2395reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/166https://doi.org/10.29021/spdv.71.2.166https://revista.spdv.com.pt/index.php/spdv/article/view/166/149Cabral, RitaBrinca, AnaVieira, RicardoMariano, AngelinaTellechea, ÓscarFigueiredo, Américoinfo:eu-repo/semantics/openAccess2022-10-06T12:34:43Zoai:ojs.revista.spdv.com.pt:article/166Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T10:30:36.224302Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv MERKEL CELL CARCINOMA – REPORT OF 7 CASES
CARCINOMA DE CÉLULAS DE MERKEL – REVISÃO DE 7 CASOS
title MERKEL CELL CARCINOMA – REPORT OF 7 CASES
spellingShingle MERKEL CELL CARCINOMA – REPORT OF 7 CASES
Cabral, Rita
Carcinoma
Merkel cell
Skin neoplasms
neuroendocrine
Carcinoma de células de Merkel
Carcinoma neuro-endócrino
title_short MERKEL CELL CARCINOMA – REPORT OF 7 CASES
title_full MERKEL CELL CARCINOMA – REPORT OF 7 CASES
title_fullStr MERKEL CELL CARCINOMA – REPORT OF 7 CASES
title_full_unstemmed MERKEL CELL CARCINOMA – REPORT OF 7 CASES
title_sort MERKEL CELL CARCINOMA – REPORT OF 7 CASES
author Cabral, Rita
author_facet Cabral, Rita
Brinca, Ana
Vieira, Ricardo
Mariano, Angelina
Tellechea, Óscar
Figueiredo, Américo
author_role author
author2 Brinca, Ana
Vieira, Ricardo
Mariano, Angelina
Tellechea, Óscar
Figueiredo, Américo
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Cabral, Rita
Brinca, Ana
Vieira, Ricardo
Mariano, Angelina
Tellechea, Óscar
Figueiredo, Américo
dc.subject.por.fl_str_mv Carcinoma
Merkel cell
Skin neoplasms
neuroendocrine
Carcinoma de células de Merkel
Carcinoma neuro-endócrino
topic Carcinoma
Merkel cell
Skin neoplasms
neuroendocrine
Carcinoma de células de Merkel
Carcinoma neuro-endócrino
description Introduction: Merkel cell carcinoma is a rare, aggressive cutaneous neuroendocrine carcinoma that affects primarily elderly people. Patients present with a rapidly growing nodule, preferably located at the head, neck and limbs. Merkel cell carcinoma as a propensity for local recurrence and regional lymph node metastases and wide local excision is the initial consensual approach. The role of lymph node dissection, radiation therapy and chemotherapy is not yet clearly established. Material and Methods: The aim of this retrospective study was to evaluate Merkel cell carcinoma patients followed in our department between the years 2000 and 2009, regarding sex, age, race, clinical features, location, stage, associated malignancies, treatment and evolution.  Results: Our data are consistent with the literature, namely regarding age, associated lymphoproliferative disease and high local recurrence and mortality rates.
publishDate 2014
dc.date.none.fl_str_mv 2014-06-24T00:00:00Z
dc.type.driver.fl_str_mv journal article
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.71.2.166
oai:ojs.revista.spdv.com.pt:article/166
url https://doi.org/10.29021/spdv.71.2.166
identifier_str_mv oai:ojs.revista.spdv.com.pt:article/166
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/166
https://doi.org/10.29021/spdv.71.2.166
https://revista.spdv.com.pt/index.php/spdv/article/view/166/149
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 71 No 2 (2013): Abril-Junho; 171-176
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 71 n. 2 (2013): Abril-Junho; 171-176
2182-2409
2182-2395
reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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