The effectiveness and tolerability of atropine eye drops for myopia control in non-Asian regions

Bibliographic Details
Main Author: Simonaviciute, Dovile
Publication Date: 2023
Other Authors: Grzybowski, Andrzej, Lanca, Carla, Pang, Chi Pui, Gelzinis, Arvydas, Zemaitiene, Reda
Format: Other
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/152050
Summary: Publisher Copyright: © 2023 by the authors.
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spelling The effectiveness and tolerability of atropine eye drops for myopia control in non-Asian regionsatropine eye dropsmyopia controlmyopia progressionmyopia treatmentMedicine(all)Publisher Copyright: © 2023 by the authors.Myopia is the most common ocular disorder worldwide with an increasing prevalence over the past few decades. It is a refractive error associated with excessive growth of the eyeball. Individuals with myopia, especially high myopia, are prone to develop sight-threatening complications. Currently, atropine is the only drug that is used to slow myopia progression in clinical practice. However, there are still areas of uncertainty such as treatment strategy, optimal concentration when considering risk–benefit ratio and active treatment period. Since the prevalence of myopia is much higher in Asian countries, most of the research on myopia control has been conducted in Asia. Data on the efficacy and tolerability to atropine eye drops in the non-Asian population remains limited. In this review, we summarize the results of published clinical trials on the effectiveness and tolerability of atropine eye drops for myopia control in non-Asian regions. The efficacy was evaluated by the mean change in spherical equivalent (SE) or axial length (AL). The tolerability of atropine eye drops was analyzed based on patients complains and adverse events. The results of this review suggest that 0.01% atropine eye drops are effective in non-Asian regions achieving less side effects compared to 0.5% concentration.Comprehensive Health Research Centre (CHRC) - Pólo ENSPCentro de Investigação em Saúde Pública (CISP/PHRC)Escola Nacional de Saúde Pública (ENSP)RUNSimonaviciute, DovileGrzybowski, AndrzejLanca, CarlaPang, Chi PuiGelzinis, ArvydasZemaitiene, Reda2023-04-21T22:21:33Z2023-032023-03-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttp://hdl.handle.net/10362/152050eng2077-0383PURE: 59105185https://doi.org/10.3390/jcm12062314info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T18:11:02Zoai:run.unl.pt:10362/152050Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:41:20.690595Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv The effectiveness and tolerability of atropine eye drops for myopia control in non-Asian regions
title The effectiveness and tolerability of atropine eye drops for myopia control in non-Asian regions
spellingShingle The effectiveness and tolerability of atropine eye drops for myopia control in non-Asian regions
Simonaviciute, Dovile
atropine eye drops
myopia control
myopia progression
myopia treatment
Medicine(all)
title_short The effectiveness and tolerability of atropine eye drops for myopia control in non-Asian regions
title_full The effectiveness and tolerability of atropine eye drops for myopia control in non-Asian regions
title_fullStr The effectiveness and tolerability of atropine eye drops for myopia control in non-Asian regions
title_full_unstemmed The effectiveness and tolerability of atropine eye drops for myopia control in non-Asian regions
title_sort The effectiveness and tolerability of atropine eye drops for myopia control in non-Asian regions
author Simonaviciute, Dovile
author_facet Simonaviciute, Dovile
Grzybowski, Andrzej
Lanca, Carla
Pang, Chi Pui
Gelzinis, Arvydas
Zemaitiene, Reda
author_role author
author2 Grzybowski, Andrzej
Lanca, Carla
Pang, Chi Pui
Gelzinis, Arvydas
Zemaitiene, Reda
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Comprehensive Health Research Centre (CHRC) - Pólo ENSP
Centro de Investigação em Saúde Pública (CISP/PHRC)
Escola Nacional de Saúde Pública (ENSP)
RUN
dc.contributor.author.fl_str_mv Simonaviciute, Dovile
Grzybowski, Andrzej
Lanca, Carla
Pang, Chi Pui
Gelzinis, Arvydas
Zemaitiene, Reda
dc.subject.por.fl_str_mv atropine eye drops
myopia control
myopia progression
myopia treatment
Medicine(all)
topic atropine eye drops
myopia control
myopia progression
myopia treatment
Medicine(all)
description Publisher Copyright: © 2023 by the authors.
publishDate 2023
dc.date.none.fl_str_mv 2023-04-21T22:21:33Z
2023-03
2023-03-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/152050
url http://hdl.handle.net/10362/152050
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2077-0383
PURE: 59105185
https://doi.org/10.3390/jcm12062314
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eu_rights_str_mv openAccess
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