The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell lines

Bibliographic Details
Main Author: Soares, S.
Publication Date: 2021
Other Authors: Guerreiro, S.G., Sales, M.G.F., Correa-Duarte, M., Fernandes, Rúben
Language: por
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.22/25128
Summary: Gold nanoparticles (AuNP) can be applied in medicine to treat many diseases, such as cancer. Over the years, they have attracted a lot of interest for therapies. In this study, we synthetized three different shapes of gold nanoparticles – spherical, stars and rods and analyzed their cytotoxicity in prostate cancer cell lines (PC3, DU145 and LNCaP). Cells were treated with different concentrations of gold nanoparticles, from 0 to 1.0 mM during 24h. The results showed that gold nanoparticles were nontoxic to concentration until 1.0 mM.
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spelling The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell linesGold nanoparticlesCytotoxicityIn vitro assayProstate cancerGold nanoparticles (AuNP) can be applied in medicine to treat many diseases, such as cancer. Over the years, they have attracted a lot of interest for therapies. In this study, we synthetized three different shapes of gold nanoparticles – spherical, stars and rods and analyzed their cytotoxicity in prostate cancer cell lines (PC3, DU145 and LNCaP). Cells were treated with different concentrations of gold nanoparticles, from 0 to 1.0 mM during 24h. The results showed that gold nanoparticles were nontoxic to concentration until 1.0 mM.INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia IndustrialREPOSITÓRIO P.PORTOSoares, S.Guerreiro, S.G.Sales, M.G.F.Correa-Duarte, M.Fernandes, Rúben2024-03-05T14:35:07Z2021-022021-02-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10400.22/25128por978-972-8826-34-5info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-07T10:27:24Zoai:recipp.ipp.pt:10400.22/25128Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T00:55:32.490641Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell lines
title The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell lines
spellingShingle The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell lines
Soares, S.
Gold nanoparticles
Cytotoxicity
In vitro assay
Prostate cancer
title_short The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell lines
title_full The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell lines
title_fullStr The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell lines
title_full_unstemmed The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell lines
title_sort The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell lines
author Soares, S.
author_facet Soares, S.
Guerreiro, S.G.
Sales, M.G.F.
Correa-Duarte, M.
Fernandes, Rúben
author_role author
author2 Guerreiro, S.G.
Sales, M.G.F.
Correa-Duarte, M.
Fernandes, Rúben
author2_role author
author
author
author
dc.contributor.none.fl_str_mv REPOSITÓRIO P.PORTO
dc.contributor.author.fl_str_mv Soares, S.
Guerreiro, S.G.
Sales, M.G.F.
Correa-Duarte, M.
Fernandes, Rúben
dc.subject.por.fl_str_mv Gold nanoparticles
Cytotoxicity
In vitro assay
Prostate cancer
topic Gold nanoparticles
Cytotoxicity
In vitro assay
Prostate cancer
description Gold nanoparticles (AuNP) can be applied in medicine to treat many diseases, such as cancer. Over the years, they have attracted a lot of interest for therapies. In this study, we synthetized three different shapes of gold nanoparticles – spherical, stars and rods and analyzed their cytotoxicity in prostate cancer cell lines (PC3, DU145 and LNCaP). Cells were treated with different concentrations of gold nanoparticles, from 0 to 1.0 mM during 24h. The results showed that gold nanoparticles were nontoxic to concentration until 1.0 mM.
publishDate 2021
dc.date.none.fl_str_mv 2021-02
2021-02-01T00:00:00Z
2024-03-05T14:35:07Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/25128
url http://hdl.handle.net/10400.22/25128
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 978-972-8826-34-5
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial
publisher.none.fl_str_mv INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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