Personalized dynamic phantom of the right and left ventricles based on patient-specific anatomy for echocardiography studies — Preliminary results

• Main Author: Fonseca, João Luís Gomes
• Publication Date: 2018
• Other Authors: Morais, Pedro André Gonçalves, Queirós, Sandro Filipe Monteiro, Veloso, Fernando, Pinho, Antonio C. M., Fonseca, Jaime C., Correia-Pinto, Jorge, Vilaça, João L.
• Language: eng
• Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
• Download full: http://hdl.handle.net/1822/58201
• topic: Patient-specific; Phantom; PVA-C; Manufacturing; Echocardiography; Ciências Médicas::Medicina Básica; Ciências Médicas::Biotecnologia Médica; Ciências Naturais::Ciências da Computação e da Informação; Science & Technology

Dynamic phantoms of the heart are becoming a reality, with their use spread across both medical and research fields. Their purpose is to mimic the cardiac anatomy, as well as its motion. This work aims to create a dynamic, ultrasound-compatible, realistic and flexible phantom of the left and right ventricles, with application in the diagnosis, planning, treatment and training in the cardiovascular field for studies using echocardiography. Here, we focus on its design and production with polyvinyl alcohol cryogel (PVA-C), to be assembled with a pump and an electromechanical (E/M) system in a water tank. Based on a patient-specific anatomical model and produced using a 3D printing technique and molding, the PVA-C phantom mimics the ventricles' natural anatomy and material properties, while the pump and E/M systems mimic the natural movements and pressures. The PVA-C phantom was assessed by imaging and measuring it using a four-dimensional ultrasound machine. The PVA-C phantom demonstrated to be a versatile option to produce patient-specific biventricular models, preserving their shape after manufacturing and presenting good echogenic properties. Both chambers were clearly seen in the ultrasound images, together with the interventricular septum and the myocardial wall. Automated left ventricle measures revealed a decrease of its volume with regard to the designed model (98 ml to 74 ml). Overall, the preliminary results are satisfactory and encourage its use for the abovementioned purposes