Prodrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systems

Bibliographic Details
Main Author: Olim, Filipe
Publication Date: 2020
Other Authors: Neves, Ana Rute, Wang, Zhao, Sun, Jingjing, Tomás, Helena, Sheng, Ruilong
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.13/3820
Summary: Using natural lipids to covalently connect with antitumor agents to construct lipid-based molecular prodrugs and their nanosystems is a promising research frontier for sustainable medicinal chemistry, nanobiotechnology and tumor chemotherapy. This paper reviewed recent progress of lipid-based doxorubicin (molecular) prodrugs and their nanodelivery systems, including lipid-doxorubicin prodrugs, stimuli-responsive lipid-doxorubicin prodrugs, and lipid-doxorubicin prodrug-based drug co-delivery nanosystems. Additionally, possible future research outlooks in this field were also discussed.
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network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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spelling Prodrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systemsLipidDoxorubicinProdrugsStimuli-responsiveDrug co-deliveryNanosystems.Faculdade de Ciências Exatas e da EngenhariaCentro de Química da MadeiraUsing natural lipids to covalently connect with antitumor agents to construct lipid-based molecular prodrugs and their nanosystems is a promising research frontier for sustainable medicinal chemistry, nanobiotechnology and tumor chemotherapy. This paper reviewed recent progress of lipid-based doxorubicin (molecular) prodrugs and their nanodelivery systems, including lipid-doxorubicin prodrugs, stimuli-responsive lipid-doxorubicin prodrugs, and lipid-doxorubicin prodrug-based drug co-delivery nanosystems. Additionally, possible future research outlooks in this field were also discussed.Medicine ResearchDigitUMaOlim, FilipeNeves, Ana RuteWang, ZhaoSun, JingjingTomás, HelenaSheng, Ruilong2021-11-16T14:22:44Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.13/3820eng10.21127/yaoyimr20200013info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-24T17:05:18Zoai:digituma.uma.pt:10400.13/3820Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T20:46:56.809390Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Prodrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systems
title Prodrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systems
spellingShingle Prodrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systems
Olim, Filipe
Lipid
Doxorubicin
Prodrugs
Stimuli-responsive
Drug co-delivery
Nanosystems
.
Faculdade de Ciências Exatas e da Engenharia
Centro de Química da Madeira
title_short Prodrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systems
title_full Prodrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systems
title_fullStr Prodrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systems
title_full_unstemmed Prodrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systems
title_sort Prodrug Systems (I): Lipid-based Doxorubicin Prodrugs and their nanodelivery systems
author Olim, Filipe
author_facet Olim, Filipe
Neves, Ana Rute
Wang, Zhao
Sun, Jingjing
Tomás, Helena
Sheng, Ruilong
author_role author
author2 Neves, Ana Rute
Wang, Zhao
Sun, Jingjing
Tomás, Helena
Sheng, Ruilong
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv DigitUMa
dc.contributor.author.fl_str_mv Olim, Filipe
Neves, Ana Rute
Wang, Zhao
Sun, Jingjing
Tomás, Helena
Sheng, Ruilong
dc.subject.por.fl_str_mv Lipid
Doxorubicin
Prodrugs
Stimuli-responsive
Drug co-delivery
Nanosystems
.
Faculdade de Ciências Exatas e da Engenharia
Centro de Química da Madeira
topic Lipid
Doxorubicin
Prodrugs
Stimuli-responsive
Drug co-delivery
Nanosystems
.
Faculdade de Ciências Exatas e da Engenharia
Centro de Química da Madeira
description Using natural lipids to covalently connect with antitumor agents to construct lipid-based molecular prodrugs and their nanosystems is a promising research frontier for sustainable medicinal chemistry, nanobiotechnology and tumor chemotherapy. This paper reviewed recent progress of lipid-based doxorubicin (molecular) prodrugs and their nanodelivery systems, including lipid-doxorubicin prodrugs, stimuli-responsive lipid-doxorubicin prodrugs, and lipid-doxorubicin prodrug-based drug co-delivery nanosystems. Additionally, possible future research outlooks in this field were also discussed.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
2021-11-16T14:22:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.13/3820
url http://hdl.handle.net/10400.13/3820
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.21127/yaoyimr20200013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Medicine Research
publisher.none.fl_str_mv Medicine Research
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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