Development of magnetic/plasmonic nickel ferrite/gold nanoparticles covered with lipid bilayers for applications in combined cancer therapy

Detalhes bibliográficos
Autor(a) principal: Rodrigues, Ana Rita Oliveira
Data de Publicação: 2019
Outros Autores: Rio, Irina S. R., Castanheira, Elisabete M. S., Coutinho, Paulo J. G.
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: https://hdl.handle.net/1822/60730
Resumo: In this work, magnetic/plasmonic nanoparticles of nickel ferrite/gold were prepared and characterized, including core/shell nanoparticles (with a nickel ferrite magnetic core and a gold plasmonic shell) and nickel ferrite nanoparticles decorated with gold nanoparticles. In order to develop applications in combined cancer therapy, the prepared nanoparticles were covered with a lipid bilayer, these systems being able to transport drugs. The heating capabilities of the nanosystems were evaluated through the fluorescence quenching of the dye rhodamine B incorporated in the lipid bilayer upon excitation with a light source. The developed multifunctional nanosystems have shown promising results for application combined cancer therapy (chemo/phototherapy).
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spelling Development of magnetic/plasmonic nickel ferrite/gold nanoparticles covered with lipid bilayers for applications in combined cancer therapyMagnetic/plasmonic nanoparticlesMagnetoliposomesDrug deliveryCancer therapyEngenharia e Tecnologia::NanotecnologiaIn this work, magnetic/plasmonic nanoparticles of nickel ferrite/gold were prepared and characterized, including core/shell nanoparticles (with a nickel ferrite magnetic core and a gold plasmonic shell) and nickel ferrite nanoparticles decorated with gold nanoparticles. In order to develop applications in combined cancer therapy, the prepared nanoparticles were covered with a lipid bilayer, these systems being able to transport drugs. The heating capabilities of the nanosystems were evaluated through the fluorescence quenching of the dye rhodamine B incorporated in the lipid bilayer upon excitation with a light source. The developed multifunctional nanosystems have shown promising results for application combined cancer therapy (chemo/phototherapy).UID/FIS/04650/2019Sociedade Portuguesa de Óptica e FotónicaUniversidade do MinhoRodrigues, Ana Rita OliveiraRio, Irina S. R.Castanheira, Elisabete M. S.Coutinho, Paulo J. G.20192019-01-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/1822/60730enginfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-11T04:20:36Zoai:repositorium.sdum.uminho.pt:1822/60730Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T14:45:55.385187Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Development of magnetic/plasmonic nickel ferrite/gold nanoparticles covered with lipid bilayers for applications in combined cancer therapy
title Development of magnetic/plasmonic nickel ferrite/gold nanoparticles covered with lipid bilayers for applications in combined cancer therapy
spellingShingle Development of magnetic/plasmonic nickel ferrite/gold nanoparticles covered with lipid bilayers for applications in combined cancer therapy
Rodrigues, Ana Rita Oliveira
Magnetic/plasmonic nanoparticles
Magnetoliposomes
Drug delivery
Cancer therapy
Engenharia e Tecnologia::Nanotecnologia
title_short Development of magnetic/plasmonic nickel ferrite/gold nanoparticles covered with lipid bilayers for applications in combined cancer therapy
title_full Development of magnetic/plasmonic nickel ferrite/gold nanoparticles covered with lipid bilayers for applications in combined cancer therapy
title_fullStr Development of magnetic/plasmonic nickel ferrite/gold nanoparticles covered with lipid bilayers for applications in combined cancer therapy
title_full_unstemmed Development of magnetic/plasmonic nickel ferrite/gold nanoparticles covered with lipid bilayers for applications in combined cancer therapy
title_sort Development of magnetic/plasmonic nickel ferrite/gold nanoparticles covered with lipid bilayers for applications in combined cancer therapy
author Rodrigues, Ana Rita Oliveira
author_facet Rodrigues, Ana Rita Oliveira
Rio, Irina S. R.
Castanheira, Elisabete M. S.
Coutinho, Paulo J. G.
author_role author
author2 Rio, Irina S. R.
Castanheira, Elisabete M. S.
Coutinho, Paulo J. G.
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Rodrigues, Ana Rita Oliveira
Rio, Irina S. R.
Castanheira, Elisabete M. S.
Coutinho, Paulo J. G.
dc.subject.por.fl_str_mv Magnetic/plasmonic nanoparticles
Magnetoliposomes
Drug delivery
Cancer therapy
Engenharia e Tecnologia::Nanotecnologia
topic Magnetic/plasmonic nanoparticles
Magnetoliposomes
Drug delivery
Cancer therapy
Engenharia e Tecnologia::Nanotecnologia
description In this work, magnetic/plasmonic nanoparticles of nickel ferrite/gold were prepared and characterized, including core/shell nanoparticles (with a nickel ferrite magnetic core and a gold plasmonic shell) and nickel ferrite nanoparticles decorated with gold nanoparticles. In order to develop applications in combined cancer therapy, the prepared nanoparticles were covered with a lipid bilayer, these systems being able to transport drugs. The heating capabilities of the nanosystems were evaluated through the fluorescence quenching of the dye rhodamine B incorporated in the lipid bilayer upon excitation with a light source. The developed multifunctional nanosystems have shown promising results for application combined cancer therapy (chemo/phototherapy).
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01T00:00:00Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/60730
url https://hdl.handle.net/1822/60730
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Óptica e Fotónica
publisher.none.fl_str_mv Sociedade Portuguesa de Óptica e Fotónica
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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