Tofacitinib: An Option for Acute Severe Ulcerative Colitis?

Bibliographic Details
Main Author: Santos,Sara
Publication Date: 2022
Other Authors: Gamelas,Verónica, Saraiva,Rita, Simões,Guilherme, Saiote,Joana, Ramos,Jaime
Format: Report
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452022000200056
Summary: Abstract Tofacitinib has emerged as a new option for ulcerative colitis. Its rapid absorption, metabolism, and clinical improvement make it an interesting option for rescue therapy in acute severe ulcerative colitis (ASUC), a situation with limited therapeutic options in patients with a long-term disease course and multiple drug failure. The management of ASUC in this setting becomes challenging, underlying the need for new drugs and data on their efficacy and safety. We describe 2 cases of acute episodes in which tofacitinib was used as a rescue therapy.
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spelling Tofacitinib: An Option for Acute Severe Ulcerative Colitis?Acute severe ulcerative colitisTofacitinibAbstract Tofacitinib has emerged as a new option for ulcerative colitis. Its rapid absorption, metabolism, and clinical improvement make it an interesting option for rescue therapy in acute severe ulcerative colitis (ASUC), a situation with limited therapeutic options in patients with a long-term disease course and multiple drug failure. The management of ASUC in this setting becomes challenging, underlying the need for new drugs and data on their efficacy and safety. We describe 2 cases of acute episodes in which tofacitinib was used as a rescue therapy.Sociedade Portuguesa de Gastrenterologia2022-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452022000200056GE-Portuguese Journal of Gastroenterology v.29 n.2 2022reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452022000200056Santos,SaraGamelas,VerónicaSaraiva,RitaSimões,GuilhermeSaiote,JoanaRamos,Jaimeinfo:eu-repo/semantics/openAccess2024-02-06T17:34:18Zoai:scielo:S2341-45452022000200056Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T13:21:08.605543Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
title Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
spellingShingle Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
Santos,Sara
Acute severe ulcerative colitis
Tofacitinib
title_short Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
title_full Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
title_fullStr Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
title_full_unstemmed Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
title_sort Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
author Santos,Sara
author_facet Santos,Sara
Gamelas,Verónica
Saraiva,Rita
Simões,Guilherme
Saiote,Joana
Ramos,Jaime
author_role author
author2 Gamelas,Verónica
Saraiva,Rita
Simões,Guilherme
Saiote,Joana
Ramos,Jaime
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Santos,Sara
Gamelas,Verónica
Saraiva,Rita
Simões,Guilherme
Saiote,Joana
Ramos,Jaime
dc.subject.por.fl_str_mv Acute severe ulcerative colitis
Tofacitinib
topic Acute severe ulcerative colitis
Tofacitinib
description Abstract Tofacitinib has emerged as a new option for ulcerative colitis. Its rapid absorption, metabolism, and clinical improvement make it an interesting option for rescue therapy in acute severe ulcerative colitis (ASUC), a situation with limited therapeutic options in patients with a long-term disease course and multiple drug failure. The management of ASUC in this setting becomes challenging, underlying the need for new drugs and data on their efficacy and safety. We describe 2 cases of acute episodes in which tofacitinib was used as a rescue therapy.
publishDate 2022
dc.date.none.fl_str_mv 2022-04-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452022000200056
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452022000200056
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452022000200056
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Gastrenterologia
publisher.none.fl_str_mv Sociedade Portuguesa de Gastrenterologia
dc.source.none.fl_str_mv GE-Portuguese Journal of Gastroenterology v.29 n.2 2022
reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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