Paper-based approach for cancer biomarker MMP7 detection using quantum dots and molecularly imprinted polymers

Bibliographic Details
Main Author: Oliveira, Pedro
Publication Date: 2024
Other Authors: Piloto, Ana Margarida L.
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.22/26380
Summary: (Introduction) Preliminary investigation using lab-on-paper Molecular Imprinted Polymers (MIPs) paired with Quantum Dots (QDs) to detect Matrix Metalloproteinase-7 (MMP7) using image processing to quantify fluorescence and area with a CMOS sensor reflex camera. MMP7 is critical in pancreatic tumor formation, which has the lowest survival rate among malignant malignancies. High levels of the MMP7 in blood have been associated to a poor prognosis and limited survival in patients. CdTe Quantum Dots (CdTe@MPA QDs) are luminescent nanoparticles with narrow emission spectra, enabling for exceptional sensitive detection of biomarkers.Combination of MIPs with CdTe MPA-capped provide selectivitive for biomiarker.
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spelling Paper-based approach for cancer biomarker MMP7 detection using quantum dots and molecularly imprinted polymersQuantum dotsPancreatic cancer diagnosisPolymers(Introduction) Preliminary investigation using lab-on-paper Molecular Imprinted Polymers (MIPs) paired with Quantum Dots (QDs) to detect Matrix Metalloproteinase-7 (MMP7) using image processing to quantify fluorescence and area with a CMOS sensor reflex camera. MMP7 is critical in pancreatic tumor formation, which has the lowest survival rate among malignant malignancies. High levels of the MMP7 in blood have been associated to a poor prognosis and limited survival in patients. CdTe Quantum Dots (CdTe@MPA QDs) are luminescent nanoparticles with narrow emission spectra, enabling for exceptional sensitive detection of biomarkers.Combination of MIPs with CdTe MPA-capped provide selectivitive for biomiarker.REPOSITÓRIO P.PORTOOliveira, PedroPiloto, Ana Margarida L.2024-11-11T15:39:25Z20242024-01-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10400.22/26380enginfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-07T10:26:41Zoai:recipp.ipp.pt:10400.22/26380Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T00:54:45.861241Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Paper-based approach for cancer biomarker MMP7 detection using quantum dots and molecularly imprinted polymers
title Paper-based approach for cancer biomarker MMP7 detection using quantum dots and molecularly imprinted polymers
spellingShingle Paper-based approach for cancer biomarker MMP7 detection using quantum dots and molecularly imprinted polymers
Oliveira, Pedro
Quantum dots
Pancreatic cancer diagnosis
Polymers
title_short Paper-based approach for cancer biomarker MMP7 detection using quantum dots and molecularly imprinted polymers
title_full Paper-based approach for cancer biomarker MMP7 detection using quantum dots and molecularly imprinted polymers
title_fullStr Paper-based approach for cancer biomarker MMP7 detection using quantum dots and molecularly imprinted polymers
title_full_unstemmed Paper-based approach for cancer biomarker MMP7 detection using quantum dots and molecularly imprinted polymers
title_sort Paper-based approach for cancer biomarker MMP7 detection using quantum dots and molecularly imprinted polymers
author Oliveira, Pedro
author_facet Oliveira, Pedro
Piloto, Ana Margarida L.
author_role author
author2 Piloto, Ana Margarida L.
author2_role author
dc.contributor.none.fl_str_mv REPOSITÓRIO P.PORTO
dc.contributor.author.fl_str_mv Oliveira, Pedro
Piloto, Ana Margarida L.
dc.subject.por.fl_str_mv Quantum dots
Pancreatic cancer diagnosis
Polymers
topic Quantum dots
Pancreatic cancer diagnosis
Polymers
description (Introduction) Preliminary investigation using lab-on-paper Molecular Imprinted Polymers (MIPs) paired with Quantum Dots (QDs) to detect Matrix Metalloproteinase-7 (MMP7) using image processing to quantify fluorescence and area with a CMOS sensor reflex camera. MMP7 is critical in pancreatic tumor formation, which has the lowest survival rate among malignant malignancies. High levels of the MMP7 in blood have been associated to a poor prognosis and limited survival in patients. CdTe Quantum Dots (CdTe@MPA QDs) are luminescent nanoparticles with narrow emission spectra, enabling for exceptional sensitive detection of biomarkers.Combination of MIPs with CdTe MPA-capped provide selectivitive for biomiarker.
publishDate 2024
dc.date.none.fl_str_mv 2024-11-11T15:39:25Z
2024
2024-01-01T00:00:00Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/26380
url http://hdl.handle.net/10400.22/26380
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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