Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients

Bibliographic Details
Main Author: Silva, Ana Paula
Publication Date: 2019
Other Authors: Mendes, Filipa, Carias, Eduarda, Baptista Gonçalves, Rui, Fragoso, André, Dias, Carolina, Tavares, Nelson, Mendonça Café, Hugo, Santos, Nélio, Rato, Fátima, Neves, Pedro Leão, Almeida, Edgar
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.1/12480
Summary: Research over the past decade has focused on the role of Klotho as a cardio protective agent that prevents the effects of aging on the heart and reduces the burden of cardiovascular disease CVD. The role of the interaction between fibroblast growth factor 23-(FGF-23)/Klotho in Klotho-mediated actions is still under debate. The main objective was to ascertain the potential use of plasmatic Klotho and FGF23 as markers for CKD-associated cardiac disease and mortality.
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spelling Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patientsKlothoFGF-23CKDCVDLVMIResearch over the past decade has focused on the role of Klotho as a cardio protective agent that prevents the effects of aging on the heart and reduces the burden of cardiovascular disease CVD. The role of the interaction between fibroblast growth factor 23-(FGF-23)/Klotho in Klotho-mediated actions is still under debate. The main objective was to ascertain the potential use of plasmatic Klotho and FGF23 as markers for CKD-associated cardiac disease and mortality.MDPISapientiaSilva, Ana PaulaMendes, FilipaCarias, EduardaBaptista Gonçalves, RuiFragoso, AndréDias, CarolinaTavares, NelsonMendonça Café, HugoSantos, NélioRato, FátimaNeves, Pedro LeãoAlmeida, Edgar2019-05-03T14:09:14Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/12480eng1422-006710.3390/ijms20071536info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-18T17:35:21Zoai:sapientia.ualg.pt:10400.1/12480Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T20:27:56.331139Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
title Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
spellingShingle Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
Silva, Ana Paula
Klotho
FGF-23
CKD
CVD
LVMI
title_short Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
title_full Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
title_fullStr Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
title_full_unstemmed Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
title_sort Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disease in type 2 diabetic patients
author Silva, Ana Paula
author_facet Silva, Ana Paula
Mendes, Filipa
Carias, Eduarda
Baptista Gonçalves, Rui
Fragoso, André
Dias, Carolina
Tavares, Nelson
Mendonça Café, Hugo
Santos, Nélio
Rato, Fátima
Neves, Pedro Leão
Almeida, Edgar
author_role author
author2 Mendes, Filipa
Carias, Eduarda
Baptista Gonçalves, Rui
Fragoso, André
Dias, Carolina
Tavares, Nelson
Mendonça Café, Hugo
Santos, Nélio
Rato, Fátima
Neves, Pedro Leão
Almeida, Edgar
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Sapientia
dc.contributor.author.fl_str_mv Silva, Ana Paula
Mendes, Filipa
Carias, Eduarda
Baptista Gonçalves, Rui
Fragoso, André
Dias, Carolina
Tavares, Nelson
Mendonça Café, Hugo
Santos, Nélio
Rato, Fátima
Neves, Pedro Leão
Almeida, Edgar
dc.subject.por.fl_str_mv Klotho
FGF-23
CKD
CVD
LVMI
topic Klotho
FGF-23
CKD
CVD
LVMI
description Research over the past decade has focused on the role of Klotho as a cardio protective agent that prevents the effects of aging on the heart and reduces the burden of cardiovascular disease CVD. The role of the interaction between fibroblast growth factor 23-(FGF-23)/Klotho in Klotho-mediated actions is still under debate. The main objective was to ascertain the potential use of plasmatic Klotho and FGF23 as markers for CKD-associated cardiac disease and mortality.
publishDate 2019
dc.date.none.fl_str_mv 2019-05-03T14:09:14Z
2019
2019-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.1/12480
url http://hdl.handle.net/10400.1/12480
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1422-0067
10.3390/ijms20071536
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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