The action of acetyl-L-carnitine in dopaminergic neurotransmission
Main Author: | |
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Publication Date: | 2014 |
Other Authors: | , , |
Language: | eng |
Source: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
Download full: | http://hdl.handle.net/10400.22/14948 |
Summary: | Acetyl-L-Carnitine (ALC) has been described as playing a neuroprotective effect against a variety of substances. However, the molecular mechanisms underlying its action, particularly regarding the induction of changes in neurotransmitter system, are still not fully understood. Using both a cell line and an animal model of exposure to methamphetamine (METH), we aim to contribute to clarify the mechanism by which the administration of ALC alters neurotransmitter release. |
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The action of acetyl-L-carnitine in dopaminergic neurotransmissionacetyl-L-carnitinedopaminergicAcetyl-L-Carnitine (ALC) has been described as playing a neuroprotective effect against a variety of substances. However, the molecular mechanisms underlying its action, particularly regarding the induction of changes in neurotransmitter system, are still not fully understood. Using both a cell line and an animal model of exposure to methamphetamine (METH), we aim to contribute to clarify the mechanism by which the administration of ALC alters neurotransmitter release.REPOSITÓRIO P.PORTOCunha, LídiaSzigeti, KrisztianMathe, DomokosMetello, Luis2019-11-26T13:08:15Z20142014-01-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10400.22/14948enginfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-07T10:05:51Zoai:recipp.ipp.pt:10400.22/14948Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T00:32:00.144050Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
dc.title.none.fl_str_mv |
The action of acetyl-L-carnitine in dopaminergic neurotransmission |
title |
The action of acetyl-L-carnitine in dopaminergic neurotransmission |
spellingShingle |
The action of acetyl-L-carnitine in dopaminergic neurotransmission Cunha, Lídia acetyl-L-carnitine dopaminergic |
title_short |
The action of acetyl-L-carnitine in dopaminergic neurotransmission |
title_full |
The action of acetyl-L-carnitine in dopaminergic neurotransmission |
title_fullStr |
The action of acetyl-L-carnitine in dopaminergic neurotransmission |
title_full_unstemmed |
The action of acetyl-L-carnitine in dopaminergic neurotransmission |
title_sort |
The action of acetyl-L-carnitine in dopaminergic neurotransmission |
author |
Cunha, Lídia |
author_facet |
Cunha, Lídia Szigeti, Krisztian Mathe, Domokos Metello, Luis |
author_role |
author |
author2 |
Szigeti, Krisztian Mathe, Domokos Metello, Luis |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
REPOSITÓRIO P.PORTO |
dc.contributor.author.fl_str_mv |
Cunha, Lídia Szigeti, Krisztian Mathe, Domokos Metello, Luis |
dc.subject.por.fl_str_mv |
acetyl-L-carnitine dopaminergic |
topic |
acetyl-L-carnitine dopaminergic |
description |
Acetyl-L-Carnitine (ALC) has been described as playing a neuroprotective effect against a variety of substances. However, the molecular mechanisms underlying its action, particularly regarding the induction of changes in neurotransmitter system, are still not fully understood. Using both a cell line and an animal model of exposure to methamphetamine (METH), we aim to contribute to clarify the mechanism by which the administration of ALC alters neurotransmitter release. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014 2014-01-01T00:00:00Z 2019-11-26T13:08:15Z |
dc.type.driver.fl_str_mv |
conference object |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.22/14948 |
url |
http://hdl.handle.net/10400.22/14948 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
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Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia |
repository.mail.fl_str_mv |
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