Blood Pressure Variability in Acute Ischemic Stroke: The Role of Early Recanalization

• Main Author: Martins, AI
• Publication Date: 2018
• Other Authors: Sargento-Freitas, J, Jesus-Ribeiro, J, Correia, I, Cardoso, L, Gomes, JP, Gonçalves, M, Costa, R, Silva, F, Galego, O, Nunes, C, Beato-Coelho, J, Varela, R, Machado, C, Rodrigues, B, Santo, GC, Cunha, L
• Format: Article
• Language: eng
• Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
• Download full: http://hdl.handle.net/10400.4/2262
• topic: Pressão Arterial; Procedimentos Endovasculares; Acidente Vascular Cerebral; Resultado do Tratamento

We performed a retrospective study with the aim of investigating the association between blood pressure (BP) variability in the first 24 h after ischemic stroke and functional outcome, regarding arterial recanalization status. A total of 674 patients diagnosed with acute stroke and treated with revascularization therapies were enrolled. Systolic and diastolic BP values of the first 24 h after stroke were collected and their variation quantified through standard deviation. Recanalization state was evaluated at 6 h and clinical outcome at 3 months was assessed by modified Rankin Scale. In multivariate analyses systolic BP variability in the first 24 h post-stroke showed an association with 3 months clinical outcome in the whole population and non-recanalyzed patients. In recanalyzed patients, BP variability did not show a significant association with functional outcome.