Multimorbidity and disease severity by age groups, in inpatients : cross-sectional study

Bibliographic Details
Main Author: Broeiro-Gonçalves, Paula
Publication Date: 2019
Other Authors: Nogueira, Paulo Jorge, Aguiar, Pedro
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10451/44056
Summary: © 2019 The Author(s). Published by S. Karger AG, Basel on behalf of NOVA National School of Public Health.
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spelling Multimorbidity and disease severity by age groups, in inpatients : cross-sectional studyMultimorbilidade e gravidade da doença por grupos etários, em pacientes internados : estudo transversalMultimorbidityComorbidityDisease burdenDisease severity© 2019 The Author(s). Published by S. Karger AG, Basel on behalf of NOVA National School of Public Health.Introduction: Multimorbidity (MM) by age groups curves behaviour and its relationship with disease severity are not well established. Considering the Charlson Index as a prognosis instrument to measure disease severity, the objectives were to characterise the MM and its severity through the Charlson index in Portuguese inpatients. Methods: A cross-sectional, descriptive study with an analytical component was drawn through data exported from the hospitalisations Homogeneous Diagnostic Groups database of the Portuguese-NHS during the year 2015. The study included 22 chronic health conditions: the 15 predicted in the Charlson index and 7 more (hypertension, obesity, dyslipidaemia, osteoarthritis, osteoporosis, anxiety and depression). The bi and multivariable analyses were performed through the generalised linear model considering binary logistic regression. In the analysis, the IBM SPSS version 24.0 tool was used. Results: A total of 800,376 hospitalisations were analysed, from which 42% (336,398) corresponds to males and 58% (463,978) to females. The average age of the sample was 59.8 years, being higher in men (62.34 years) than in women (57.95 years). The mean number of diagnostics per person was 1.6, being greater in men (1.8). Disease severity was also higher in males. The greatest disease severity (Charlson >5) occurred at middle-aged (between 55 and 74 years). Throughout life behaviour of the average number of conditions and the average Charlson index without adjustment for age is similar. By the weight attributed to age, the Charlson index age-adjusted shows a sharper tendency of elevation after the forty years. The distribution by age groups of the age-adjusted Charlson index, categorised according to the cut-offs defined in the methodology (cut-off 0 to <5; cut-off 5 to <9; cut-off ≥9), showed an abrupt growth for the cut-off ≥9 at 55/59 years, peaking at 75/79 years, while for cut-off 5 at <9 the most marked growth occurs at 65/69 and the peak about 5 years later than for the cut-off ≥9. After the 90 years old all measures averages (MM and severity disease) suffer a decline. Discussion: The results suggest that the greatest disease severity are male associated and occurred at middle ages. There was an association between any MM measure and the Charlson index. The MM curves behaviour showed a decline in nonagenary age, suggesting healthy people live longer. Questioned if the MM and its severity is not a middle age health issue. As limitations, we identified its cross-sectional design and the omission of socioeconomic information and the use of the same medical conditions to measure MM and disease severity. Other studies and analysis models should explore the complexity of the MM phenomenon and its impact on long life.Karger Publishers Open AccessRepositório da Universidade de LisboaBroeiro-Gonçalves, PaulaNogueira, Paulo JorgeAguiar, Pedro2020-07-21T09:21:12Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/44056engPortuguese Journal of Public Health, 37(1), 1-72504-313710.1159/0005001192504-3145info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T14:21:47Zoai:repositorio.ulisboa.pt:10451/44056Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T03:09:37.602210Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Multimorbidity and disease severity by age groups, in inpatients : cross-sectional study
Multimorbilidade e gravidade da doença por grupos etários, em pacientes internados : estudo transversal
title Multimorbidity and disease severity by age groups, in inpatients : cross-sectional study
spellingShingle Multimorbidity and disease severity by age groups, in inpatients : cross-sectional study
Broeiro-Gonçalves, Paula
Multimorbidity
Comorbidity
Disease burden
Disease severity
title_short Multimorbidity and disease severity by age groups, in inpatients : cross-sectional study
title_full Multimorbidity and disease severity by age groups, in inpatients : cross-sectional study
title_fullStr Multimorbidity and disease severity by age groups, in inpatients : cross-sectional study
title_full_unstemmed Multimorbidity and disease severity by age groups, in inpatients : cross-sectional study
title_sort Multimorbidity and disease severity by age groups, in inpatients : cross-sectional study
author Broeiro-Gonçalves, Paula
author_facet Broeiro-Gonçalves, Paula
Nogueira, Paulo Jorge
Aguiar, Pedro
author_role author
author2 Nogueira, Paulo Jorge
Aguiar, Pedro
author2_role author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Broeiro-Gonçalves, Paula
Nogueira, Paulo Jorge
Aguiar, Pedro
dc.subject.por.fl_str_mv Multimorbidity
Comorbidity
Disease burden
Disease severity
topic Multimorbidity
Comorbidity
Disease burden
Disease severity
description © 2019 The Author(s). Published by S. Karger AG, Basel on behalf of NOVA National School of Public Health.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01T00:00:00Z
2020-07-21T09:21:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/44056
url http://hdl.handle.net/10451/44056
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Portuguese Journal of Public Health, 37(1), 1-7
2504-3137
10.1159/000500119
2504-3145
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Karger Publishers Open Access
publisher.none.fl_str_mv Karger Publishers Open Access
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833601615244820480

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