Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic review

Detalhes bibliográficos
Autor(a) principal: Correia, Inês
Data de Publicação: 2024
Outros Autores: Oliveira, Patrícia, Antunes, Maria Luz, Raimundo, Maria da Graça, Moreira, Ana Catarina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: http://hdl.handle.net/10451/64333
Resumo: © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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spelling Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic reviewCrohn’s diseaseCrohn’s disease exclusion dietExclusive enteral nutritionPartial enteral nutritionRemission© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).Crohn's disease (CD) is an inflammatory bowel disease. Previous research has explored the impact of diet on CD, as specific dietary components can influence gut microbiota and immune responses, contributing to damage in the gastrointestinal tract. The Crohn's Disease Exclusion Diet (CDED) is based on an exclusion diet; it is a recent dietary approach that is often used alongside partial enteral nutrition (PEN) and aims to induce disease remission by excluding certain dietary components. This study assesses the current evidence for the effectiveness of the CDED + PEN in achieving remission in both children and adults with active CD. Our systematic review followed PRISMA recommendations and was registered in PROSPERO with CRD number 42022335076. The searched databases were PubMed/MEDLINE, Cochrane Library, Scopus, and Web of Science. The included studies were analyzed using Rayyan software, and the risk of bias was assessed with Cochrane RevMan 5.0 software. The primary assessed outcome was clinical remission, evaluated with validated questionnaire scores such as PCDAI, CDAI, or HBI. All analyzed papers yielded promising results. Notably, the CDED + PEN demonstrated better tolerance than exclusive enteral nutrition (EEN), resulting in higher adherence rates. Therefore, the CDED + PEN appears to be a viable alternative for induction remission in active disease for both children and adults with CD.The H&TRC author gratefully acknowledges the FCT/MCTES national support through UIDB/05608/2020 and UIDP/05608/2020. This study was part of the MSc thesis in Clinical Nutrition of one of the authors (I.C.) (supervisor, A.C.M.; co-supervisor, G.R.) from Faculty of Medicine of Lisbon and Escola Superior de Tecnologia da Saúde de Lisboa, Lisbon, Portugal.MDPIRepositório da Universidade de LisboaCorreia, InêsOliveira, PatríciaAntunes, Maria LuzRaimundo, Maria da GraçaMoreira, Ana Catarina2024-04-16T14:53:29Z20242024-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/64333engNutrients. 2024 Mar 28;16(7):98710.3390/nu160709872072-6643info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T15:14:39Zoai:repositorio.ulisboa.pt:10451/64333Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T03:37:46.613308Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic review
title Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic review
spellingShingle Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic review
Correia, Inês
Crohn’s disease
Crohn’s disease exclusion diet
Exclusive enteral nutrition
Partial enteral nutrition
Remission
title_short Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic review
title_full Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic review
title_fullStr Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic review
title_full_unstemmed Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic review
title_sort Is there evidence of Crohn’s disease exclusion diet (CDED) in remission of active disease in children and adults? A systematic review
author Correia, Inês
author_facet Correia, Inês
Oliveira, Patrícia
Antunes, Maria Luz
Raimundo, Maria da Graça
Moreira, Ana Catarina
author_role author
author2 Oliveira, Patrícia
Antunes, Maria Luz
Raimundo, Maria da Graça
Moreira, Ana Catarina
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Correia, Inês
Oliveira, Patrícia
Antunes, Maria Luz
Raimundo, Maria da Graça
Moreira, Ana Catarina
dc.subject.por.fl_str_mv Crohn’s disease
Crohn’s disease exclusion diet
Exclusive enteral nutrition
Partial enteral nutrition
Remission
topic Crohn’s disease
Crohn’s disease exclusion diet
Exclusive enteral nutrition
Partial enteral nutrition
Remission
description © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
publishDate 2024
dc.date.none.fl_str_mv 2024-04-16T14:53:29Z
2024
2024-01-01T00:00:00Z
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/64333
url http://hdl.handle.net/10451/64333
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language eng
dc.relation.none.fl_str_mv Nutrients. 2024 Mar 28;16(7):987
10.3390/nu16070987
2072-6643
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