Treatable traits in copd – a proposed approach

Bibliographic Details
Main Author: Cardoso, João
Publication Date: 2021
Other Authors: Ferreira, António Jorge, Guimarães, Miguel, Oliveira, Ana Sofia, Simão, Paula, Sucena, Maria
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/129672
Summary: Funding Information: Medical writing support for this article was provided by Paula Pinto, PhD, of PMA – Pharmaceutical Medicine Academy and was funded by Bial. All authors contributed equally to this work and should be considered co-first authors for this study. Funding Information: This article was funded by Bial. Bial provided all necessary scientific bibliography and funded medical writing support and publishing charges. The authors did not receive direct funding for the writing of this article. Publisher Copyright: © 2021 Cardoso et al.
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spelling Treatable traits in copd – a proposed approachCOPDFuturePhased approachPrecision medicineTreatable traits strategyPulmonary and Respiratory MedicineHealth PolicyPublic Health, Environmental and Occupational HealthSDG 3 - Good Health and Well-beingFunding Information: Medical writing support for this article was provided by Paula Pinto, PhD, of PMA – Pharmaceutical Medicine Academy and was funded by Bial. All authors contributed equally to this work and should be considered co-first authors for this study. Funding Information: This article was funded by Bial. Bial provided all necessary scientific bibliography and funded medical writing support and publishing charges. The authors did not receive direct funding for the writing of this article. Publisher Copyright: © 2021 Cardoso et al.The well-recognized individual heterogeneity within COPD patients has led to a growing interest in greater personalization in the approach of these patients. Thus, the treatable traits strategy has been proposed as a further step towards precision medicine in the management of chronic airway disease, both in stable phase and acute exacerbations. The aim of this paper is to perform a critical review on the treatable traits strategy and propose a guide to approach COPD patients in the light of this new concept. An innovative stepwise approach is proposed – a multidisciplinary model based on two distinct phases, with the potential to be implemented in both primary care and hospital settings. The first phase is the initial and focused assessment of a selected subset of treatable traits, which should be addressed in all COPD patients in both settings (primary care and hospital). As some patients may present with advanced disease at diagnosis or may progress despite this initial treatment requiring a more specialized assessment, they should progress to a second phase, in which a broader approach is recommended. Beyond stable COPD, we explore how the treatable traits strategy may be applied to reduce the risk of future exacerbations and improve the management of COPD exacerbations. Since many treatable traits have already been related to exacerbation risk, the strategy proposed here represents an opportunity to be proactive. Although it still lacks prospective validation, we believe this is the way forward for the future of the COPD approach.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNCardoso, JoãoFerreira, António JorgeGuimarães, MiguelOliveira, Ana SofiaSimão, PaulaSucena, Maria2021-12-22T23:26:01Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article16application/pdfhttp://hdl.handle.net/10362/129672eng1176-9106PURE: 35419075https://doi.org/10.2147/COPD.S330817info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T17:57:45Zoai:run.unl.pt:10362/129672Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:28:59.505810Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Treatable traits in copd – a proposed approach
title Treatable traits in copd – a proposed approach
spellingShingle Treatable traits in copd – a proposed approach
Cardoso, João
COPD
Future
Phased approach
Precision medicine
Treatable traits strategy
Pulmonary and Respiratory Medicine
Health Policy
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
title_short Treatable traits in copd – a proposed approach
title_full Treatable traits in copd – a proposed approach
title_fullStr Treatable traits in copd – a proposed approach
title_full_unstemmed Treatable traits in copd – a proposed approach
title_sort Treatable traits in copd – a proposed approach
author Cardoso, João
author_facet Cardoso, João
Ferreira, António Jorge
Guimarães, Miguel
Oliveira, Ana Sofia
Simão, Paula
Sucena, Maria
author_role author
author2 Ferreira, António Jorge
Guimarães, Miguel
Oliveira, Ana Sofia
Simão, Paula
Sucena, Maria
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Cardoso, João
Ferreira, António Jorge
Guimarães, Miguel
Oliveira, Ana Sofia
Simão, Paula
Sucena, Maria
dc.subject.por.fl_str_mv COPD
Future
Phased approach
Precision medicine
Treatable traits strategy
Pulmonary and Respiratory Medicine
Health Policy
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
topic COPD
Future
Phased approach
Precision medicine
Treatable traits strategy
Pulmonary and Respiratory Medicine
Health Policy
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
description Funding Information: Medical writing support for this article was provided by Paula Pinto, PhD, of PMA – Pharmaceutical Medicine Academy and was funded by Bial. All authors contributed equally to this work and should be considered co-first authors for this study. Funding Information: This article was funded by Bial. Bial provided all necessary scientific bibliography and funded medical writing support and publishing charges. The authors did not receive direct funding for the writing of this article. Publisher Copyright: © 2021 Cardoso et al.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-22T23:26:01Z
2021
2021-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/129672
url http://hdl.handle.net/10362/129672
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1176-9106
PURE: 35419075
https://doi.org/10.2147/COPD.S330817
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 16
application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
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reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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