Central airway obstruction
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Publication Date: | 2022 |
Other Authors: | , , , , |
Format: | Article |
Language: | eng |
Source: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
Download full: | http://hdl.handle.net/10362/134493 |
Summary: | Funding: This research was supported by Projects PEst-OE/AGR/UI0211/2011 from FCT, and COMPETE 2020, from ANI – Projetos ID&T Empresas em Copromoção, by the project “insitu.Biomas – Reinvent biomanufacturing systems by using an usability approach for in situ clinic temporary implants fabrication” with the reference POCI-01-0247-FEDER-017771, by the project “Print-on-Organs – Engineering bioinks and processes for direct printing on organs” with the reference POCI-01-0247-FEDER-033877, and by the project “Bone2Move – Development of “in vivo” experimental techniques and modelling methodologies for the evaluation of 4D scafolds for bone defect in sheep model: an integrative research approach” with the reference POCI-01-0145-FEDER-031146. Mariana Vieira Branquinho (SFRH/BD/146172/2019), Ana Catarina Sousa (SFRH/BD/146689/2019), and Rui Damásio Alvites (SFRH/BD/116118/2016), acknowledge FCT, for financial support. |
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Central airway obstructionis it time to move forward?Airway stentsCentral airway obstructionInterventional bronchologyRegenerative medicinePulmonary and Respiratory MedicineFunding: This research was supported by Projects PEst-OE/AGR/UI0211/2011 from FCT, and COMPETE 2020, from ANI – Projetos ID&T Empresas em Copromoção, by the project “insitu.Biomas – Reinvent biomanufacturing systems by using an usability approach for in situ clinic temporary implants fabrication” with the reference POCI-01-0247-FEDER-017771, by the project “Print-on-Organs – Engineering bioinks and processes for direct printing on organs” with the reference POCI-01-0247-FEDER-033877, and by the project “Bone2Move – Development of “in vivo” experimental techniques and modelling methodologies for the evaluation of 4D scafolds for bone defect in sheep model: an integrative research approach” with the reference POCI-01-0145-FEDER-031146. Mariana Vieira Branquinho (SFRH/BD/146172/2019), Ana Catarina Sousa (SFRH/BD/146689/2019), and Rui Damásio Alvites (SFRH/BD/116118/2016), acknowledge FCT, for financial support.INTRODUCTION: Central airway obstruction (CAO) represents a pathological condition that can lead to airflow limitation of the trachea, main stem bronchi, bronchus intermedius or lobar bronchus. MAIN BODY: It is a common clinical situation consensually considered under-diagnosed. Management of patients with CAO can be difficult and deciding on the best treatment approach represents a medical challenge. This work intends to review CAO classifications, causes, treatments and its therapeutic limitations, approaching benign and malign presentations. Three illustrative cases are further presented, supporting the clinical problem under review. CONCLUSION: Management of CAO still remains a challenge. The available options are not always effective nor free from complications. A new generation of costume-tailored airway stents, associated with stem cell-based therapy, could be an option in specific clinical situations.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNGuedes, FernandoBranquinho, Mariana V.Sousa, Ana C.Alvites, Rui D.Bugalho, AntónioMaurício, Ana Colette2022-03-14T23:23:15Z2022-02-192022-02-19T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/134493eng1471-2466PURE: 42090485https://doi.org/10.1186/s12890-022-01862-xinfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T18:00:09Zoai:run.unl.pt:10362/134493Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:31:03.456409Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
dc.title.none.fl_str_mv |
Central airway obstruction is it time to move forward? |
title |
Central airway obstruction |
spellingShingle |
Central airway obstruction Guedes, Fernando Airway stents Central airway obstruction Interventional bronchology Regenerative medicine Pulmonary and Respiratory Medicine |
title_short |
Central airway obstruction |
title_full |
Central airway obstruction |
title_fullStr |
Central airway obstruction |
title_full_unstemmed |
Central airway obstruction |
title_sort |
Central airway obstruction |
author |
Guedes, Fernando |
author_facet |
Guedes, Fernando Branquinho, Mariana V. Sousa, Ana C. Alvites, Rui D. Bugalho, António Maurício, Ana Colette |
author_role |
author |
author2 |
Branquinho, Mariana V. Sousa, Ana C. Alvites, Rui D. Bugalho, António Maurício, Ana Colette |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
dc.contributor.author.fl_str_mv |
Guedes, Fernando Branquinho, Mariana V. Sousa, Ana C. Alvites, Rui D. Bugalho, António Maurício, Ana Colette |
dc.subject.por.fl_str_mv |
Airway stents Central airway obstruction Interventional bronchology Regenerative medicine Pulmonary and Respiratory Medicine |
topic |
Airway stents Central airway obstruction Interventional bronchology Regenerative medicine Pulmonary and Respiratory Medicine |
description |
Funding: This research was supported by Projects PEst-OE/AGR/UI0211/2011 from FCT, and COMPETE 2020, from ANI – Projetos ID&T Empresas em Copromoção, by the project “insitu.Biomas – Reinvent biomanufacturing systems by using an usability approach for in situ clinic temporary implants fabrication” with the reference POCI-01-0247-FEDER-017771, by the project “Print-on-Organs – Engineering bioinks and processes for direct printing on organs” with the reference POCI-01-0247-FEDER-033877, and by the project “Bone2Move – Development of “in vivo” experimental techniques and modelling methodologies for the evaluation of 4D scafolds for bone defect in sheep model: an integrative research approach” with the reference POCI-01-0145-FEDER-031146. Mariana Vieira Branquinho (SFRH/BD/146172/2019), Ana Catarina Sousa (SFRH/BD/146689/2019), and Rui Damásio Alvites (SFRH/BD/116118/2016), acknowledge FCT, for financial support. |
publishDate |
2022 |
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2022-03-14T23:23:15Z 2022-02-19 2022-02-19T00:00:00Z |
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http://hdl.handle.net/10362/134493 |
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eng |
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1471-2466 PURE: 42090485 https://doi.org/10.1186/s12890-022-01862-x |
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