Main Determinants of PON1 Activity in Hemodialysis Patients

Bibliographic Details
Main Author: Ribeiro, Sandra
Publication Date: 2012
Other Authors: do Sameiro Faria, Maria, Mascarenhas-Melo, Filipa, Freitas, Isabel, Mendonca, Maria Isabel, Nascimento, Henrique, Rocha-Pereira, Petronila, Miranda, Vasco, Mendonça, Denisa, Quintanilha, Alexandre, Belo, Luís, Costa, Elísio, Reis, Flávio, Santos-Silva, Alice
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.26/35487
Summary: Cardiovascular diseases are the major cause of morbidity and mortality in hemodialysis (HD) patients. These patients present reduced paraoxonase 1 (PON1) activity that depends on genetic and non-genetic factors; however, how these factors influence PON1 activity in HD patients is poorly clarified. Our aim was to evaluate the influence of two polymorphisms and non-genetic factors on PON1 activity in HD patients.
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network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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spelling Main Determinants of PON1 Activity in Hemodialysis PatientsAdiponectinAgedAged, 80 and overAnemiaAryldialkylphosphataseBiomarkersC-Reactive ProteinEnzyme ActivationErythropoietinFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsInflammationInterleukin-6Kidney Failure, ChronicLipidsMaleMiddle AgedPolymorphism, GeneticPrognosisRisk FactorsRenal DialysisMadeira IslandPortugalCardiovascular diseases are the major cause of morbidity and mortality in hemodialysis (HD) patients. These patients present reduced paraoxonase 1 (PON1) activity that depends on genetic and non-genetic factors; however, how these factors influence PON1 activity in HD patients is poorly clarified. Our aim was to evaluate the influence of two polymorphisms and non-genetic factors on PON1 activity in HD patients.KargerRepositório ComumRibeiro, Sandrado Sameiro Faria, MariaMascarenhas-Melo, FilipaFreitas, IsabelMendonca, Maria IsabelNascimento, HenriqueRocha-Pereira, PetronilaMiranda, VascoMendonça, DenisaQuintanilha, AlexandreBelo, LuísCosta, ElísioReis, FlávioSantos-Silva, Alice2021-02-15T15:31:43Z20122012-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/35487eng10.1159/000342235info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-04-11T02:17:14Zoai:comum.rcaap.pt:10400.26/35487Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T06:21:58.581378Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Main Determinants of PON1 Activity in Hemodialysis Patients
title Main Determinants of PON1 Activity in Hemodialysis Patients
spellingShingle Main Determinants of PON1 Activity in Hemodialysis Patients
Ribeiro, Sandra
Adiponectin
Aged
Aged, 80 and over
Anemia
Aryldialkylphosphatase
Biomarkers
C-Reactive Protein
Enzyme Activation
Erythropoietin
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Inflammation
Interleukin-6
Kidney Failure, Chronic
Lipids
Male
Middle Aged
Polymorphism, Genetic
Prognosis
Risk Factors
Renal Dialysis
Madeira Island
Portugal
title_short Main Determinants of PON1 Activity in Hemodialysis Patients
title_full Main Determinants of PON1 Activity in Hemodialysis Patients
title_fullStr Main Determinants of PON1 Activity in Hemodialysis Patients
title_full_unstemmed Main Determinants of PON1 Activity in Hemodialysis Patients
title_sort Main Determinants of PON1 Activity in Hemodialysis Patients
author Ribeiro, Sandra
author_facet Ribeiro, Sandra
do Sameiro Faria, Maria
Mascarenhas-Melo, Filipa
Freitas, Isabel
Mendonca, Maria Isabel
Nascimento, Henrique
Rocha-Pereira, Petronila
Miranda, Vasco
Mendonça, Denisa
Quintanilha, Alexandre
Belo, Luís
Costa, Elísio
Reis, Flávio
Santos-Silva, Alice
author_role author
author2 do Sameiro Faria, Maria
Mascarenhas-Melo, Filipa
Freitas, Isabel
Mendonca, Maria Isabel
Nascimento, Henrique
Rocha-Pereira, Petronila
Miranda, Vasco
Mendonça, Denisa
Quintanilha, Alexandre
Belo, Luís
Costa, Elísio
Reis, Flávio
Santos-Silva, Alice
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Ribeiro, Sandra
do Sameiro Faria, Maria
Mascarenhas-Melo, Filipa
Freitas, Isabel
Mendonca, Maria Isabel
Nascimento, Henrique
Rocha-Pereira, Petronila
Miranda, Vasco
Mendonça, Denisa
Quintanilha, Alexandre
Belo, Luís
Costa, Elísio
Reis, Flávio
Santos-Silva, Alice
dc.subject.por.fl_str_mv Adiponectin
Aged
Aged, 80 and over
Anemia
Aryldialkylphosphatase
Biomarkers
C-Reactive Protein
Enzyme Activation
Erythropoietin
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Inflammation
Interleukin-6
Kidney Failure, Chronic
Lipids
Male
Middle Aged
Polymorphism, Genetic
Prognosis
Risk Factors
Renal Dialysis
Madeira Island
Portugal
topic Adiponectin
Aged
Aged, 80 and over
Anemia
Aryldialkylphosphatase
Biomarkers
C-Reactive Protein
Enzyme Activation
Erythropoietin
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Inflammation
Interleukin-6
Kidney Failure, Chronic
Lipids
Male
Middle Aged
Polymorphism, Genetic
Prognosis
Risk Factors
Renal Dialysis
Madeira Island
Portugal
description Cardiovascular diseases are the major cause of morbidity and mortality in hemodialysis (HD) patients. These patients present reduced paraoxonase 1 (PON1) activity that depends on genetic and non-genetic factors; however, how these factors influence PON1 activity in HD patients is poorly clarified. Our aim was to evaluate the influence of two polymorphisms and non-genetic factors on PON1 activity in HD patients.
publishDate 2012
dc.date.none.fl_str_mv 2012
2012-01-01T00:00:00Z
2021-02-15T15:31:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/35487
url http://hdl.handle.net/10400.26/35487
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1159/000342235
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Karger
publisher.none.fl_str_mv Karger
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833602665901195264

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