Extracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host–pathogen communication

Bibliographic Details
Main Author: Sabatke, Bruna
Publication Date: 2024
Other Authors: Rossi, Izadora Volpato, Sana, Abel, Bonato, Leticia Bassani, Ramirez, Marcel I.
Format: Article
Language: eng
Source: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1111/mmi.15168
Download full: https://arca.fiocruz.br/handle/icict/67542
Summary: CAPES (Funding Code 001); Conselho Nacional de Desenvolvimento Científico e Tecnológico, Grant/Award Number: 301719/2016-0, 307314/2018-9 and 404717/2016-0; FIOCRUZ and Basic Parasitology Program AUXPE 2041/2011 (CAPES) Brazil.
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spelling Sabatke, BrunaRossi, Izadora VolpatoSana, AbelBonato, Leticia BassaniRamirez, Marcel I.2024-12-12T12:18:10Z2024-12-12T12:18:10Z2024SABATKE, B. et al. Extracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host-pathogen communication. Molecular Microbiology, v. 122, n. 5, p. 613-629, 2024.1365-2958https://arca.fiocruz.br/handle/icict/6754210.1111/mmi.15168CAPES (Funding Code 001); Conselho Nacional de Desenvolvimento Científico e Tecnológico, Grant/Award Number: 301719/2016-0, 307314/2018-9 and 404717/2016-0; FIOCRUZ and Basic Parasitology Program AUXPE 2041/2011 (CAPES) Brazil.Federal University of Paraná. Graduate Program in Microbiology, Pathology and Parasitology. Curitiba, PR, Brasil / Fundação Oswaldo Cruz. Instituto Carlos Chagas. Grupo de Pesquisa em Vesículas Extracelulares e Interações Parasita-Hospedeiro. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Grupo de Pesquisa em Vesículas Extracelulares e Interações Parasita-Hospedeiro. Curitiba, PR, Brasil / Federal University of Paraná. Graduate Program in Cell and Molecular Biology. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Grupo de Pesquisa em Vesículas Extracelulares e Interações Parasita-Hospedeiro. Curitiba, PR, Brasil / Federal University of Paraná. Graduate Program in Cell and Molecular Biology. Curitiba, PR, Brasil.Federal University of Paraná. Graduate Program in Microbiology, Pathology and Parasitology. Curitiba, PR, Brasil / Fundação Oswaldo Cruz. Instituto Carlos Chagas. Grupo de Pesquisa em Vesículas Extracelulares e Interações Parasita-Hospedeiro. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Grupo de Pesquisa em Vesículas Extracelulares e Interações Parasita-Hospedeiro. Curitiba, PR, Brasil.The study of host–pathogen interactions has increased considerably in recent decades. This intercellular communication has been mediated by extracellular vesicles (EVs) that play an important role during the interaction. EVs are particles of lipid bilayer and described in different types of cells, eukaryotic or prokaryotic. Depending on their biogenesis they are described as exosomes (derived from multivesicular bodies) and microvesicles (derived from the plasma membrane). The EVs carry biomolecules, including nucleic acids, lipids, and proteins that can be released or internalized by other cells in different pathways (endocytosis, macropinocytosis, phagocytosis, or membrane fusion) in the process described as uptake. The balance between biogenesis and uptake of EVs could modify physiological and pathophysiological processes of the cell. This review is focusing on the dynamic roles of release and capture of EVs during host–pathogen interaction. We also do a critical analysis of methodologies for obtaining and analyzing EVs. Finally, we draw attention to critical points to be considered in EV biogenesis and uptake studies.engWilleyBiogêneseExossomosVesículas extracelularesMicrovesículasInteração Parasita-hospedeiroBiogenesisExosomesExtracellular vesiclesHost–pathogen interactionMicrovesiclesUptakeVesículas ExtracelularesInterações Hospedeiro-ParasitaExtracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host–pathogen communicationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://arca.fiocruz.br/bitstreams/0bad5e02-c841-4460-97a0-3bf2162ac132/download5a560609d32a3863062d77ff32785d58MD51falseAnonymousREADORIGINALve_Bruna_Sabatke_etal_ICC_2024.pdfve_Bruna_Sabatke_etal_ICC_2024.pdfapplication/pdf5069782https://arca.fiocruz.br/bitstreams/869d89a6-9c8a-4f87-a3ba-6c6ef383b1e7/downloadd3472d73bceded10c7d6570597723eb3MD52trueAnonymousREADTEXTve_Bruna_Sabatke_etal_ICC_2024.pdf.txtve_Bruna_Sabatke_etal_ICC_2024.pdf.txtExtracted texttext/plain100791https://arca.fiocruz.br/bitstreams/1da0a1d8-75f8-46f6-ac14-28fe7ff2c8df/download633bea55a4b82a8dd9036a4db0854e70MD55falseAnonymousREADTHUMBNAILve_Bruna_Sabatke_etal_ICC_2024.pdf.jpgve_Bruna_Sabatke_etal_ICC_2024.pdf.jpgGenerated Thumbnailimage/jpeg5931https://arca.fiocruz.br/bitstreams/d5ded17a-17b9-4d34-9160-efa5729c1fac/downloadd2a29fa0deed2c8e377b1c36d179d926MD56falseAnonymousREADicict/675422025-08-03 15:46:37.532open.accessoai:arca.fiocruz.br:icict/67542https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-08-03T18:46:37Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.none.fl_str_mv Extracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host–pathogen communication
title Extracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host–pathogen communication
spellingShingle Extracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host–pathogen communication
Sabatke, Bruna
Biogênese
Exossomos
Vesículas extracelulares
Microvesículas
Interação Parasita-hospedeiro
Biogenesis
Exosomes
Extracellular vesicles
Host–pathogen interaction
Microvesicles
Uptake
Vesículas Extracelulares
Interações Hospedeiro-Parasita
title_short Extracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host–pathogen communication
title_full Extracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host–pathogen communication
title_fullStr Extracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host–pathogen communication
title_full_unstemmed Extracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host–pathogen communication
title_sort Extracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host–pathogen communication
author Sabatke, Bruna
author_facet Sabatke, Bruna
Rossi, Izadora Volpato
Sana, Abel
Bonato, Leticia Bassani
Ramirez, Marcel I.
author_role author
author2 Rossi, Izadora Volpato
Sana, Abel
Bonato, Leticia Bassani
Ramirez, Marcel I.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Sabatke, Bruna
Rossi, Izadora Volpato
Sana, Abel
Bonato, Leticia Bassani
Ramirez, Marcel I.
dc.subject.other.none.fl_str_mv Biogênese
Exossomos
Vesículas extracelulares
Microvesículas
Interação Parasita-hospedeiro
topic Biogênese
Exossomos
Vesículas extracelulares
Microvesículas
Interação Parasita-hospedeiro
Biogenesis
Exosomes
Extracellular vesicles
Host–pathogen interaction
Microvesicles
Uptake
Vesículas Extracelulares
Interações Hospedeiro-Parasita
dc.subject.en.none.fl_str_mv Biogenesis
Exosomes
Extracellular vesicles
Host–pathogen interaction
Microvesicles
Uptake
dc.subject.decs.none.fl_str_mv Vesículas Extracelulares
Interações Hospedeiro-Parasita
description CAPES (Funding Code 001); Conselho Nacional de Desenvolvimento Científico e Tecnológico, Grant/Award Number: 301719/2016-0, 307314/2018-9 and 404717/2016-0; FIOCRUZ and Basic Parasitology Program AUXPE 2041/2011 (CAPES) Brazil.
publishDate 2024
dc.date.accessioned.fl_str_mv 2024-12-12T12:18:10Z
dc.date.available.fl_str_mv 2024-12-12T12:18:10Z
dc.date.issued.fl_str_mv 2024
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SABATKE, B. et al. Extracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host-pathogen communication. Molecular Microbiology, v. 122, n. 5, p. 613-629, 2024.
dc.identifier.uri.fl_str_mv https://arca.fiocruz.br/handle/icict/67542
dc.identifier.issn.none.fl_str_mv 1365-2958
dc.identifier.doi.none.fl_str_mv 10.1111/mmi.15168
identifier_str_mv SABATKE, B. et al. Extracellular vesicles biogenesis and uptake concepts: a comprehensive guide to studying host-pathogen communication. Molecular Microbiology, v. 122, n. 5, p. 613-629, 2024.
1365-2958
10.1111/mmi.15168
url https://arca.fiocruz.br/handle/icict/67542
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Willey
publisher.none.fl_str_mv Willey
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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