Potent activity of a high concentration of chemical ozone against antibiotic-resistant bacteria
| Main Author: | |
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| Publication Date: | 2022 |
| Other Authors: | , , , , , |
| Format: | Conference object |
| Language: | eng |
| Source: | Repositório Institucional da FIOCRUZ (ARCA) |
| Download full: | https://arca.fiocruz.br/handle/icict/60983 |
Summary: | Produção científica do Laboratório de Ultraestrutura Celular. |
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Rangel, KaryneCabral, Fellipe O.Lechuga, Guilherme C.Carvalho, João P. R. S.Villas-Bôas, Maria H. S.Midlej, VictorDe-Simone, Salvatore G.2023-10-30T14:05:35Z2023-10-30T14:05:35Z2022RANGEL, Karine et al. Potent Activity of a High Concentration of Chemical Ozone against Antibiotic-Resistant Bacteria. In: CONGRESSO BRASILEIRO DE MICROBIOLOGIA, 32., 2023, Foz do Iguaçu: SBM, 2023. 1 p.https://arca.fiocruz.br/handle/icict/60983Produção científica do Laboratório de Ultraestrutura Celular.Federal Fluminense University. Biology Institute. Department of Molecular and Cellular Biology. Post-Graduation Program in Science and Biotechnology. Niterói, RJ, Brazil.Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Instituto Nacional de Ciência e Tecnologia de Inovação em Doenças de Populações Negligenciadas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Instituto Nacional de Ciência e Tecnologia de Inovação em Doenças de Populações Negligenciadas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Microbiologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Ultraestrutura Celular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Instituto Nacional de Ciência e Tecnologia de Inovação em Doenças de Populações Negligenciadas. Rio de Janeiro, RJ, Brasil.Background: Health care-associated infections (HAIs) are a significant public health problem worldwide, favoring multidrug-resistant (MDR) microorganisms. The SARS-CoV-2 infection was negatively associated with the increase in antimicrobial resistance, and the ESKAPE group had the most significant impact on HAIs. The study evaluated the bactericidal effect of a high concentration of O3 gas on some reference and ESKAPE bacteria. Material and Methods: Four standard strains and four clinical or environmental MDR strains were exposed to elevated ozone doses at different concentrations and times. Bacterial inactivation (growth and cultivability) was investigated using colony counts and resazurin as metabolic indicators. Scanning electron microscopy (SEM) was performed. Results: The culture exposure to a high level of O3 inhibited the growth of all bacterial strains tested with a statistically significant reduction in colony count compared to the control group. The cell viability of S. aureus (MRSA) (99.6%) and P. aeruginosa (XDR) (29.2%) was reduced considerably, and SEM showed damage to bacteria after O3 treatment Conclusion: The impact of HAIs can be easily dampened by the widespread use of ozone in ICUs. This product usually degrades into molecular oxygen and has a low toxicity compared to other sanitization products. However, high doses of ozone were able to interfere with the growth of all strains studied, evidencing that ozone-based decontamination approaches may represent the future of hospital cleaning methods.engFiocruz/INCQSOzônioBactéria patogênicaResistência antimicrobianaSEMPatógenos ESKAPEActividade antimicrobianaOzonePathogenic bacteriaAntimicrobial resistanceSEMESKAPE pathogensAntimicrobial activityPotent activity of a high concentration of chemical ozone against antibiotic-resistant bacteriainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://arca.fiocruz.br/bitstreams/4b5b21d2-de74-4154-a308-b277693e26a7/download5a560609d32a3863062d77ff32785d58MD51falseAnonymousREADORIGINAL2023_poster_32cbm_karine-rangel.pdf2023_poster_32cbm_karine-rangel.pdfArtigo principalapplication/pdf656472https://arca.fiocruz.br/bitstreams/fb9e29d3-ef95-4246-8212-25e5647d8121/download7234b68e310579b6681f0c3d6e686cb0MD52trueAnonymousREADTEXT2023_poster_32cbm_karine-rangel.pdf.txt2023_poster_32cbm_karine-rangel.pdf.txtExtracted texttext/plain7657https://arca.fiocruz.br/bitstreams/371aedd2-8b0d-49b6-8bca-9cc1c0900104/download66fe0901a20bbcd6d18d9a0ff372c5d5MD55falseAnonymousREADTHUMBNAIL2023_poster_32cbm_karine-rangel.pdf.jpg2023_poster_32cbm_karine-rangel.pdf.jpgGenerated Thumbnailimage/jpeg7175https://arca.fiocruz.br/bitstreams/7f1a7cb7-e44d-4a22-b988-f6610e5d0a07/download6a586185c194ca6ad0891c70c5f9c45dMD56falseAnonymousREADicict/609832025-07-30 02:07:48.731open.accessoai:arca.fiocruz.br:icict/60983https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-07-30T05:07:48Repositório Institucional da FIOCRUZ (ARCA) - 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| dc.title.none.fl_str_mv |
Potent activity of a high concentration of chemical ozone against antibiotic-resistant bacteria |
| title |
Potent activity of a high concentration of chemical ozone against antibiotic-resistant bacteria |
| spellingShingle |
Potent activity of a high concentration of chemical ozone against antibiotic-resistant bacteria Rangel, Karyne Ozônio Bactéria patogênica Resistência antimicrobiana SEM Patógenos ESKAPE Actividade antimicrobiana Ozone Pathogenic bacteria Antimicrobial resistance SEM ESKAPE pathogens Antimicrobial activity |
| title_short |
Potent activity of a high concentration of chemical ozone against antibiotic-resistant bacteria |
| title_full |
Potent activity of a high concentration of chemical ozone against antibiotic-resistant bacteria |
| title_fullStr |
Potent activity of a high concentration of chemical ozone against antibiotic-resistant bacteria |
| title_full_unstemmed |
Potent activity of a high concentration of chemical ozone against antibiotic-resistant bacteria |
| title_sort |
Potent activity of a high concentration of chemical ozone against antibiotic-resistant bacteria |
| author |
Rangel, Karyne |
| author_facet |
Rangel, Karyne Cabral, Fellipe O. Lechuga, Guilherme C. Carvalho, João P. R. S. Villas-Bôas, Maria H. S. Midlej, Victor De-Simone, Salvatore G. |
| author_role |
author |
| author2 |
Cabral, Fellipe O. Lechuga, Guilherme C. Carvalho, João P. R. S. Villas-Bôas, Maria H. S. Midlej, Victor De-Simone, Salvatore G. |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Rangel, Karyne Cabral, Fellipe O. Lechuga, Guilherme C. Carvalho, João P. R. S. Villas-Bôas, Maria H. S. Midlej, Victor De-Simone, Salvatore G. |
| dc.subject.other.none.fl_str_mv |
Ozônio Bactéria patogênica Resistência antimicrobiana SEM Patógenos ESKAPE Actividade antimicrobiana |
| topic |
Ozônio Bactéria patogênica Resistência antimicrobiana SEM Patógenos ESKAPE Actividade antimicrobiana Ozone Pathogenic bacteria Antimicrobial resistance SEM ESKAPE pathogens Antimicrobial activity |
| dc.subject.en.none.fl_str_mv |
Ozone Pathogenic bacteria Antimicrobial resistance SEM ESKAPE pathogens Antimicrobial activity |
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Produção científica do Laboratório de Ultraestrutura Celular. |
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2022 |
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2022 |
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2023-10-30T14:05:35Z |
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2023-10-30T14:05:35Z |
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RANGEL, Karine et al. Potent Activity of a High Concentration of Chemical Ozone against Antibiotic-Resistant Bacteria. In: CONGRESSO BRASILEIRO DE MICROBIOLOGIA, 32., 2023, Foz do Iguaçu: SBM, 2023. 1 p. |
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https://arca.fiocruz.br/handle/icict/60983 |
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RANGEL, Karine et al. Potent Activity of a High Concentration of Chemical Ozone against Antibiotic-Resistant Bacteria. In: CONGRESSO BRASILEIRO DE MICROBIOLOGIA, 32., 2023, Foz do Iguaçu: SBM, 2023. 1 p. |
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Fiocruz/INCQS |
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Fiocruz/INCQS |
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