Specific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansi

Bibliographic Details
Main Author: Queiroz, Adriana O.
Publication Date: 2001
Other Authors: Legey, Ana P., Xavier, Samanta C. C., Jansen, Ana M.
Format: Article
Language: eng
Source: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1590/S0074-02762001000700014
Download full: https://arca.fiocruz.br/handle/icict/44157
Summary: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia; Rio de Janeiro, RJ, Brasil.
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spelling Queiroz, Adriana O.Legey, Ana P.Xavier, Samanta C. C.Jansen, Ana M.2020-10-23T20:39:44Z2020-10-23T20:39:44Z2001QUEIROZ, Adriana O. et al. Specific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansi. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 96, n. 7, p. 965-972, Oct. 2001.0074-0276https://arca.fiocruz.br/handle/icict/4415710.1590/S0074-027620010007000141678-8060engFiocruz/IOCTrypanosoma evansiRatos WistarReconhecimento antigênicoTeste indireto de anticorpos fluorescentesTrypanosoma evansiWistar ratsAntigenic recognitionIndirect fluorescent antibody testSpecific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansiinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia; Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia; Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia; Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia; Rio de Janeiro, RJ, Brasil."Mal de Cadeiras", an enzootic disease caused by Trypanosoma evansi, is one of the most important trypanosomiases in the Brazilian Pantanal region. The disease affects mainly horses, which are widely used in extensive cattle production, an activity of greatest economical significance for the region. The parasite also infects sylvan (coatis and capybaras) and domestic (dogs) animals, respectively considered wild and domestic reservoirs of T. evansi. For a better understanding of the interaction of T. evansi with its rodent host, we evaluated the differences in the specific antibody level patterns and in the parasitic peptides recognition patterns of experimentally infected Wistar rats. The rats experimentally infected with T. evansi isolates obtained from coatis, dogs and horses were submitted to indirect immunofluorescence test (IgM e IgG) and Western blotting. The serological titers for IgM and IgG ranged between 1:40 and 1:160. The most recognized polypeptide profiles were in a range of 17 and 74 kDa. Our data suggest that the humoral immune response in Wistar rats is not sufficient for granting an effective control of T. evansi infections.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://arca.fiocruz.br/bitstreams/b19fc054-6dc1-49b9-beb8-79488d0dd3f9/download5a560609d32a3863062d77ff32785d58MD51falseAnonymousREADORIGINALAdrianaQueiroz_SamantaXavier_etal_IOC_2001.pdfAdrianaQueiroz_SamantaXavier_etal_IOC_2001.pdfapplication/pdf149403https://arca.fiocruz.br/bitstreams/63654587-c4d5-487c-b881-733dcb93987e/download086f8540777ffd1794bd2448ebf014aaMD52trueAnonymousREADTEXTAdrianaQueiroz_SamantaXavier_etal_IOC_2001.pdf.txtAdrianaQueiroz_SamantaXavier_etal_IOC_2001.pdf.txtExtracted texttext/plain30089https://arca.fiocruz.br/bitstreams/8e6d0951-e088-4fe2-a490-66375937bf10/download4bc416f3127a7c15946fa8c3de0a8f47MD55falseAnonymousREADTHUMBNAILAdrianaQueiroz_SamantaXavier_etal_IOC_2001.pdf.jpgAdrianaQueiroz_SamantaXavier_etal_IOC_2001.pdf.jpgGenerated Thumbnailimage/jpeg6461https://arca.fiocruz.br/bitstreams/ca8bca30-269b-4396-8311-45b81fad1fe2/download63fe335c9911b7ce3e6aef66fe1bca3bMD56falseAnonymousREADicict/441572025-07-31 13:23:47.51open.accessoai:arca.fiocruz.br:icict/44157https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-07-31T16:23:47Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.none.fl_str_mv Specific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansi
title Specific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansi
spellingShingle Specific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansi
Queiroz, Adriana O.
Trypanosoma evansi
Ratos Wistar
Reconhecimento antigênico
Teste indireto de anticorpos fluorescentes
Trypanosoma evansi
Wistar rats
Antigenic recognition
Indirect fluorescent antibody test
title_short Specific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansi
title_full Specific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansi
title_fullStr Specific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansi
title_full_unstemmed Specific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansi
title_sort Specific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansi
author Queiroz, Adriana O.
author_facet Queiroz, Adriana O.
Legey, Ana P.
Xavier, Samanta C. C.
Jansen, Ana M.
author_role author
author2 Legey, Ana P.
Xavier, Samanta C. C.
Jansen, Ana M.
author2_role author
author
author
dc.contributor.author.fl_str_mv Queiroz, Adriana O.
Legey, Ana P.
Xavier, Samanta C. C.
Jansen, Ana M.
dc.subject.other.none.fl_str_mv Trypanosoma evansi
Ratos Wistar
Reconhecimento antigênico
Teste indireto de anticorpos fluorescentes
topic Trypanosoma evansi
Ratos Wistar
Reconhecimento antigênico
Teste indireto de anticorpos fluorescentes
Trypanosoma evansi
Wistar rats
Antigenic recognition
Indirect fluorescent antibody test
dc.subject.en.none.fl_str_mv Trypanosoma evansi
Wistar rats
Antigenic recognition
Indirect fluorescent antibody test
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia; Rio de Janeiro, RJ, Brasil.
publishDate 2001
dc.date.issued.fl_str_mv 2001
dc.date.accessioned.fl_str_mv 2020-10-23T20:39:44Z
dc.date.available.fl_str_mv 2020-10-23T20:39:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv QUEIROZ, Adriana O. et al. Specific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansi. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 96, n. 7, p. 965-972, Oct. 2001.
dc.identifier.uri.fl_str_mv https://arca.fiocruz.br/handle/icict/44157
dc.identifier.issn.none.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02762001000700014
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv QUEIROZ, Adriana O. et al. Specific Antibody Levels and Antigenic Recognition of Wistar Rats Inoculated with Distinct Isolates of Trypanosoma evansi. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 96, n. 7, p. 965-972, Oct. 2001.
0074-0276
10.1590/S0074-02762001000700014
1678-8060
url https://arca.fiocruz.br/handle/icict/44157
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fiocruz/IOC
publisher.none.fl_str_mv Fiocruz/IOC
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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