Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast
| Main Author: | |
|---|---|
| Publication Date: | 2024 |
| Other Authors: | , , , , , |
| Format: | Article |
| Language: | eng |
| Source: | Repositório Institucional da FIOCRUZ (ARCA) |
| DOI: | 10.1016/j.bjid.2024.103741 |
| Download full: | https://arca.fiocruz.br/handle/icict/65270 |
Summary: | Programa de Expansão da Educação Profissional – Proep/ IGM. |
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Moura Neto, José PereiraAlbuquerque, Cinthia Cristina Matheus XerezYahouédéhou, Sètondji Cocou Modeste AlexandreFrancisco, Marcos Vinicius LimaFraiji, Nelson AbrahimSiqueira, Isadora Cristina deGoncalves, Marilda Souza2024-08-06T18:26:49Z2024-08-06T18:26:49Z2024MOURA NETO, José Pereira et al. Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast. The Brazilian Journal of Infectious Diseases, v. 28, n. 2, p. 1-6, 2024.1678-4391https://arca.fiocruz.br/handle/icict/6527010.1016/j.bjid.2024.103741Programa de Expansão da Educação Profissional – Proep/ IGM.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal do Amazonas. Faculdade de Ciências Farmacêuticas. Laboratório de Análise Especializada em Biologia Molecular. Manaus, AM, Brasil / Universidade do Estado do Amazonas. Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas. Manaus, AM, Brasil.Universidade do Estado do Amazonas. Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Universidade do Estado do Amazonas. Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Sickle Cell Disease (SCD) is a hereditary disease characterized by extravascular and intravascular hemolysis and clinical variability, from mild pain to potentially life-threatening. Arboviruses include mainly Zika (ZIKV), Chikungunya (CHKV), and Dengue (DENV) virus, and are considered a public and social health problem. The present cross-sectional observational study aimed to investigate the prevalence of arbovirus infection in SCD patients from two Brazilian cities, Salvador and Manaus located in Bahia and Amazonas states respectively. A total of 409 individuals with SCD were included in the study, and 307 (75.06 %) patients tested positive for DENV-IgG, 161 (39.36 %) for ZIKV-IgG, and 60 (14.67 %) for CHIKV-IgG. Only one individual was positive for DENV-NS1 and another for DENV-IgM, both from Salvador. No individuals had positive serology for ZIKV-IgM or CHIKV-IgM. Arbovirus positivity by IgG testing revealed that the SCD group presented high frequencies in both cities. Interestingly, these differences were only statistically significant for ZIKV-IgG (p = 0.023) and CHIKV-IgG (p = 0.005) among SCD patients from Manaus. The reshaping of arbovirus from its natural habitat by humans due to disorderly urban expansion and the ease of international Mobility has been responsible for facilitating the spread of vector-borne infectious diseases in humans. We found the need for further studies on arboviruses in this population to elucidate the real association and impact, especially in acute infection. We hope that this study will contribute to improvements in the personalized clinical follow-up of SCD patients, identifying the influence of arbovirus infection in severe disease manifestations.engElsevierArbovírusZIKVDENVCHIKVDoença falciformeSalvadorManausArbovirusZIKVDENVCHIKVSickle cell diseaseSalvadorManausArbovirusZika virusDengueVírus ChikungunyaAnemia falciforme03 Saúde e Bem-EstarPrevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeastinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://arca.fiocruz.br/bitstreams/5e0fd33f-3c01-46a3-865c-04a51f2ed65c/download5a560609d32a3863062d77ff32785d58MD51falseAnonymousREADORIGINALMoura Neto, José P. - Prevalence of arboviruses in sickle cell disease patients.pdfMoura Neto, José P. - 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| dc.title.none.fl_str_mv |
Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast |
| title |
Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast |
| spellingShingle |
Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast Moura Neto, José Pereira Arbovírus ZIKV DENV CHIKV Doença falciforme Salvador Manaus Arbovirus ZIKV DENV CHIKV Sickle cell disease Salvador Manaus Arbovirus Zika virus Dengue Vírus Chikungunya Anemia falciforme 03 Saúde e Bem-Estar |
| title_short |
Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast |
| title_full |
Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast |
| title_fullStr |
Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast |
| title_full_unstemmed |
Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast |
| title_sort |
Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast |
| author |
Moura Neto, José Pereira |
| author_facet |
Moura Neto, José Pereira Albuquerque, Cinthia Cristina Matheus Xerez Yahouédéhou, Sètondji Cocou Modeste Alexandre Francisco, Marcos Vinicius Lima Fraiji, Nelson Abrahim Siqueira, Isadora Cristina de Goncalves, Marilda Souza |
| author_role |
author |
| author2 |
Albuquerque, Cinthia Cristina Matheus Xerez Yahouédéhou, Sètondji Cocou Modeste Alexandre Francisco, Marcos Vinicius Lima Fraiji, Nelson Abrahim Siqueira, Isadora Cristina de Goncalves, Marilda Souza |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Moura Neto, José Pereira Albuquerque, Cinthia Cristina Matheus Xerez Yahouédéhou, Sètondji Cocou Modeste Alexandre Francisco, Marcos Vinicius Lima Fraiji, Nelson Abrahim Siqueira, Isadora Cristina de Goncalves, Marilda Souza |
| dc.subject.other.none.fl_str_mv |
Arbovírus ZIKV DENV CHIKV Doença falciforme Salvador Manaus |
| topic |
Arbovírus ZIKV DENV CHIKV Doença falciforme Salvador Manaus Arbovirus ZIKV DENV CHIKV Sickle cell disease Salvador Manaus Arbovirus Zika virus Dengue Vírus Chikungunya Anemia falciforme 03 Saúde e Bem-Estar |
| dc.subject.en.none.fl_str_mv |
Arbovirus ZIKV DENV CHIKV Sickle cell disease Salvador Manaus |
| dc.subject.decs.none.fl_str_mv |
Arbovirus Zika virus Dengue Vírus Chikungunya Anemia falciforme |
| dc.subject.ods.none.fl_str_mv |
03 Saúde e Bem-Estar |
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Programa de Expansão da Educação Profissional – Proep/ IGM. |
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2024 |
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2024-08-06T18:26:49Z |
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2024-08-06T18:26:49Z |
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2024 |
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MOURA NETO, José Pereira et al. Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast. The Brazilian Journal of Infectious Diseases, v. 28, n. 2, p. 1-6, 2024. |
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https://arca.fiocruz.br/handle/icict/65270 |
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1678-4391 |
| dc.identifier.doi.none.fl_str_mv |
10.1016/j.bjid.2024.103741 |
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MOURA NETO, José Pereira et al. Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast. The Brazilian Journal of Infectious Diseases, v. 28, n. 2, p. 1-6, 2024. 1678-4391 10.1016/j.bjid.2024.103741 |
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Elsevier |
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Elsevier |
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