Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach

Bibliographic Details
Main Author: Cirne-Lima,Fernando K
Publication Date: 2009
Other Authors: Rosa,Aline de Souza, Kulczynski,Jane M U, Mattana,Diego S, Corezolla,Kizzy, Moreira,Luis F
Format: Article
Language: eng
Source: Revista do Colégio Brasileiro de Cirurgiões
Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912009000200007
Summary: OBJECTIVES: To determine the prevalence of Her-2/Neu-cerbb-2 in the gastric mucosa of patients with gastric adenocarcinoma in a brazilian patient group. METHODS: The immunohistochemical expression of Her-2/Neu was studied in 37 formalin-fixed paraffin-embedded tissue sections. RESULTS: The immunohistochemical reaction produced by the anti-HER-2/Neu antibody was positive in two cases (5.4%). CONCLUSION: The low prevalence of Her-2/Neu observed in these southern brazilian cases is probably due to the great number of poorly differentiated cancers in this serie.
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spelling Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomachStomach neoplasmsOncogenesImmunohistochemistryOBJECTIVES: To determine the prevalence of Her-2/Neu-cerbb-2 in the gastric mucosa of patients with gastric adenocarcinoma in a brazilian patient group. METHODS: The immunohistochemical expression of Her-2/Neu was studied in 37 formalin-fixed paraffin-embedded tissue sections. RESULTS: The immunohistochemical reaction produced by the anti-HER-2/Neu antibody was positive in two cases (5.4%). CONCLUSION: The low prevalence of Her-2/Neu observed in these southern brazilian cases is probably due to the great number of poorly differentiated cancers in this serie.Colégio Brasileiro de Cirurgiões2009-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912009000200007Revista do Colégio Brasileiro de Cirurgiões v.36 n.2 2009reponame:Revista do Colégio Brasileiro de Cirurgiõesinstname:Colégio Brasileiro de Cirurgiões (CBC)instacron:CBC10.1590/S0100-69912009000200007info:eu-repo/semantics/openAccessCirne-Lima,Fernando KRosa,Aline de SouzaKulczynski,Jane M UMattana,Diego SCorezolla,KizzyMoreira,Luis Feng2009-06-30T00:00:00Zoai:scielo:S0100-69912009000200007Revistahttp://www.scielo.br/rcbcONGhttps://old.scielo.br/oai/scielo-oai.php||revistacbc@cbc.org.br1809-45460100-6991opendoar:2009-06-30T00:00Revista do Colégio Brasileiro de Cirurgiões - Colégio Brasileiro de Cirurgiões (CBC)false
dc.title.none.fl_str_mv Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach
title Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach
spellingShingle Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach
Cirne-Lima,Fernando K
Stomach neoplasms
Oncogenes
Immunohistochemistry
title_short Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach
title_full Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach
title_fullStr Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach
title_full_unstemmed Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach
title_sort Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach
author Cirne-Lima,Fernando K
author_facet Cirne-Lima,Fernando K
Rosa,Aline de Souza
Kulczynski,Jane M U
Mattana,Diego S
Corezolla,Kizzy
Moreira,Luis F
author_role author
author2 Rosa,Aline de Souza
Kulczynski,Jane M U
Mattana,Diego S
Corezolla,Kizzy
Moreira,Luis F
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Cirne-Lima,Fernando K
Rosa,Aline de Souza
Kulczynski,Jane M U
Mattana,Diego S
Corezolla,Kizzy
Moreira,Luis F
dc.subject.por.fl_str_mv Stomach neoplasms
Oncogenes
Immunohistochemistry
topic Stomach neoplasms
Oncogenes
Immunohistochemistry
description OBJECTIVES: To determine the prevalence of Her-2/Neu-cerbb-2 in the gastric mucosa of patients with gastric adenocarcinoma in a brazilian patient group. METHODS: The immunohistochemical expression of Her-2/Neu was studied in 37 formalin-fixed paraffin-embedded tissue sections. RESULTS: The immunohistochemical reaction produced by the anti-HER-2/Neu antibody was positive in two cases (5.4%). CONCLUSION: The low prevalence of Her-2/Neu observed in these southern brazilian cases is probably due to the great number of poorly differentiated cancers in this serie.
publishDate 2009
dc.date.none.fl_str_mv 2009-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912009000200007
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-69912009000200007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Colégio Brasileiro de Cirurgiões
publisher.none.fl_str_mv Colégio Brasileiro de Cirurgiões
dc.source.none.fl_str_mv Revista do Colégio Brasileiro de Cirurgiões v.36 n.2 2009
reponame:Revista do Colégio Brasileiro de Cirurgiões
instname:Colégio Brasileiro de Cirurgiões (CBC)
instacron:CBC
instname_str Colégio Brasileiro de Cirurgiões (CBC)
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reponame_str Revista do Colégio Brasileiro de Cirurgiões
collection Revista do Colégio Brasileiro de Cirurgiões
repository.name.fl_str_mv Revista do Colégio Brasileiro de Cirurgiões - Colégio Brasileiro de Cirurgiões (CBC)
repository.mail.fl_str_mv ||revistacbc@cbc.org.br
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