Condyloma acuminatum: ts histopathological pattern

Detalhes bibliográficos
Autor(a) principal: Dias, Eliane Pedra
Data de Publicação: 1997
Outros Autores: Gouvêa, Ana Luisa Figueira, Eyer, EyerClaudia Carvalhal
Tipo de documento: Artigo
Idioma: eng
Título da fonte: São Paulo medical journal (Online)
Texto Completo: https://periodicosapm.emnuvens.com.br/spmj/article/view/2093
Resumo: Condyloma acuminatum is one of the clinical manifestations of papillomavirus infection. The classical histopathological features are already known and do not constitute a diagnostic problem. Clinically, it has been classified into growth or proliferative, full-expression, and regressive or persistent phases, with the histopathological aspects of these distinct phases being well documented in equine cutaneous papillomas. We have designed a protocol of histopathological analysis in order to investigate the possibility of identifying the evolutional phases in human condylomata acuminata. Sixty condylomata acuminata from the files of the Department of Pathology, Universidade Federal Fluminense, were studied regarding koilocytosis, paraceratosis, acantosis, basal cell hyperplasia and mono-nuclear cell infiltrate. After an individual analysis and comparison of the cases, the main differential aspects of condyloma acuminatum were: koilocytosis, transepithelial lymphocytic infiltrate and basal cell hyperplasia. Thus, condylomatous lesions can be histopathologically differentiated in three major patterns: proliferative, viral replication activity and regressive.
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spelling Condyloma acuminatum: ts histopathological patternCondyloma acuminatumkoilocytosishistopathologic patternregressionCondyloma acuminatum is one of the clinical manifestations of papillomavirus infection. The classical histopathological features are already known and do not constitute a diagnostic problem. Clinically, it has been classified into growth or proliferative, full-expression, and regressive or persistent phases, with the histopathological aspects of these distinct phases being well documented in equine cutaneous papillomas. We have designed a protocol of histopathological analysis in order to investigate the possibility of identifying the evolutional phases in human condylomata acuminata. Sixty condylomata acuminata from the files of the Department of Pathology, Universidade Federal Fluminense, were studied regarding koilocytosis, paraceratosis, acantosis, basal cell hyperplasia and mono-nuclear cell infiltrate. After an individual analysis and comparison of the cases, the main differential aspects of condyloma acuminatum were: koilocytosis, transepithelial lymphocytic infiltrate and basal cell hyperplasia. Thus, condylomatous lesions can be histopathologically differentiated in three major patterns: proliferative, viral replication activity and regressive.O condiloma acuminado corresponde à uma das manifestações clínicas da infecção pelo Papilomavirus humano. Os aspectos histopatológicos clássicos são reconhecidos de longa data não constituem problema diagnóstico. Clinicamente, já estão bem caracterizadas as fases de crescimento, de plenitude da expressão clínica e regressiva ou persistente. Os aspectos histopatológicos destas fases foram documentadas em papilomas eqüinos. Formulamos um protocolo de análise histopatológica para investigar a possibilidade de identificação das fases evolutivas em condilomas acuminados genitais. Foram estudados 60 condilomas acuminados, examinados no Serviço de Anatomia Patológica do Hospital Universitário Antonio Pedro (HUAP). Todos os casos foram revistos, avaliando-se a presença de coilocitose, hiperceratose, paraceratose, acantose, hiperplasia da basal e infiltrado inflamatório mononuclear. Após a análise individual e comparativa dos casos, identificou-se como principais aspectos diferenciais entre os vários condilomas acuminados a coilocitase, o infiltrado linfocitário transepitelial e a hiperplasia da basal. Os condilomas podem ser distinguidos, histopatologicamente, em três padrões principais: proliferativo, de atividade de replicação virótica e regressivo.São Paulo Medical JournalSão Paulo Medical Journal1997-03-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicosapm.emnuvens.com.br/spmj/article/view/2093São Paulo Medical Journal; Vol. 115 No. 2 (1997); 1383-1389São Paulo Medical Journal; v. 115 n. 2 (1997); 1383-13891806-9460reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APMenghttps://periodicosapm.emnuvens.com.br/spmj/article/view/2093/1991https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessDias, Eliane PedraGouvêa, Ana Luisa FigueiraEyer, EyerClaudia Carvalhal2023-09-27T12:26:13Zoai:ojs.diagnosticoetratamento.emnuvens.com.br:article/2093Revistahttp://www.scielo.br/spmjPUBhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2023-09-27T12:26:13São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv Condyloma acuminatum: ts histopathological pattern
title Condyloma acuminatum: ts histopathological pattern
spellingShingle Condyloma acuminatum: ts histopathological pattern
Dias, Eliane Pedra
Condyloma acuminatum
koilocytosis
histopathologic pattern
regression
title_short Condyloma acuminatum: ts histopathological pattern
title_full Condyloma acuminatum: ts histopathological pattern
title_fullStr Condyloma acuminatum: ts histopathological pattern
title_full_unstemmed Condyloma acuminatum: ts histopathological pattern
title_sort Condyloma acuminatum: ts histopathological pattern
author Dias, Eliane Pedra
author_facet Dias, Eliane Pedra
Gouvêa, Ana Luisa Figueira
Eyer, EyerClaudia Carvalhal
author_role author
author2 Gouvêa, Ana Luisa Figueira
Eyer, EyerClaudia Carvalhal
author2_role author
author
dc.contributor.author.fl_str_mv Dias, Eliane Pedra
Gouvêa, Ana Luisa Figueira
Eyer, EyerClaudia Carvalhal
dc.subject.por.fl_str_mv Condyloma acuminatum
koilocytosis
histopathologic pattern
regression
topic Condyloma acuminatum
koilocytosis
histopathologic pattern
regression
description Condyloma acuminatum is one of the clinical manifestations of papillomavirus infection. The classical histopathological features are already known and do not constitute a diagnostic problem. Clinically, it has been classified into growth or proliferative, full-expression, and regressive or persistent phases, with the histopathological aspects of these distinct phases being well documented in equine cutaneous papillomas. We have designed a protocol of histopathological analysis in order to investigate the possibility of identifying the evolutional phases in human condylomata acuminata. Sixty condylomata acuminata from the files of the Department of Pathology, Universidade Federal Fluminense, were studied regarding koilocytosis, paraceratosis, acantosis, basal cell hyperplasia and mono-nuclear cell infiltrate. After an individual analysis and comparison of the cases, the main differential aspects of condyloma acuminatum were: koilocytosis, transepithelial lymphocytic infiltrate and basal cell hyperplasia. Thus, condylomatous lesions can be histopathologically differentiated in three major patterns: proliferative, viral replication activity and regressive.
publishDate 1997
dc.date.none.fl_str_mv 1997-03-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicosapm.emnuvens.com.br/spmj/article/view/2093
url https://periodicosapm.emnuvens.com.br/spmj/article/view/2093
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicosapm.emnuvens.com.br/spmj/article/view/2093/1991
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv São Paulo Medical Journal
São Paulo Medical Journal
publisher.none.fl_str_mv São Paulo Medical Journal
São Paulo Medical Journal
dc.source.none.fl_str_mv São Paulo Medical Journal; Vol. 115 No. 2 (1997); 1383-1389
São Paulo Medical Journal; v. 115 n. 2 (1997); 1383-1389
1806-9460
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
instacron_str APM
institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
_version_ 1825135072024461312

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