Epidemiology, diagnosis, treatment, and future perspectives concerning SARS-COV-2: a review article

• Autor(a) principal: Carvalho,Arthur Ricardo Vilar Scavuzzi de
• Data de Publicação: 2020
• Outros Autores: Cezarotti Filho,Murilo Lobo, Azevedo,Pedro Cavalcanti Pires de, Silveira Filho,Robson Natario, Barbosa,Fabiano Timbó, Rocha,Thiago José Matos, Sousa-Rodrigues,Célio Fernando de, Ramos,Fernando Wagner da Silva
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista da Associação Médica Brasileira (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302020000300370
• topic: Coronavirus; Epidemiology; Signs and symptoms; Diagnosis; Therapeutics

SUMMARY The present study aimed to review the epidemiology, clinical manifestation, laboratory diagnosis, treatment, and future perspectives related to COVID-19 infections. The following electronic databases were used searched: MEDLINE, SCIELO, and LILACS. It became clear that COVID-19 infections occur through exposure to the virus, and both the immunosuppressed and healthy population appear susceptible. The clinical course of COVID-19 is still not clear, although the SARS-CoV-2 infection seems to develop with mild, influenza-like symptoms in the vast majority of subjects, i.e., 10%–15% of COVID-19 patients. Since rRT-PCR tests serve as the gold standard method to confirm a SARS-CoV-2 infection, false-negative results could hinder the prevention and control of the epidemic, particularly considering the test plays a key role in the decision for continued isolated medical observation or discharge. Our findings also indicate that a radical increase in the identification and isolation of currently undocumented infections would be needed to fully control SARS-CoV2.