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Hearing loss in acromegaly : a review

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Hlavní autor: Teixeira, Liane Sousa
Datum vydání: 2018
Další autoři: Silva, Isabelle Braz de Oliveira, Sampaio, Andre Luiz Lopes, Oliveira, Carlos Augusto Pires de, Bahamad Júnior, Fayez
Médium: Article
Jazyk: eng
Zdroj: Repositório Institucional da UnB
Download full: http://repositorio.unb.br/handle/10482/33633
http://dx.doi.org/10.1055/s-0037-1603619
Shrnutí: Introduction Acromegaly is a chronic disease caused by growth hormone (GH) excess due to a GH-secreting pituitary adenoma in most cases. There is reasonable data to presume the possible influence of chronic GH and insulin-like growth factor I (IGF-I) hyperproduction on the anatomical structures involved in normal sound perception, and on its conductive and/or sensorineural part. Objectives To review the literature about acromegaly and hearing loss. Data Synthesis A systematic literature search was performed using the MEDLINE database, including hand-searching reference lists from original articles. The search was performed using the terms hearing loss and acromegaly, and only 5 studies were found. Conclusion The results are not consistent, but led to different conclusions. Therefore, more studies with greater numbers of patients with acromegaly are needed.