Contribuição ao estudo de reações mediadas por calcogenetos Zn e Cu: hidrocalcogenação de ácidos e ésteres e síntese de sulfetos arílicos
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| Autor principal: | |
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| Data de publicació: | 2012 |
| Format: | Master thesis |
| Idioma: | por |
| Font: | Repositório Institucional da UFG |
| Download full: | http://repositorio.bc.ufg.br/tede/handle/tede/3097 |
Sumari: | This work describes some studies on the preparation of unsymmetrical diaryl thioethers catalyzed by Copper(I)-Senelenophene-2-carboxylate. The results concern to the catalyzed cross-coupling reaction between aryl halides and aryl or alkylthiols using Copper(I)-Senelenophene-2-carboxylate (CuSC) a new Cu-catalyzed one-pot protocol. The products were obtained in good to excellent yields under relatively mild reaction conditions presenting chemoselectivity and functional group tolerance. Additionally, we have developed a chemio-, regio and stereoselective synthesis of vinyl chalcogenides compounds promoted by zinc chalcogenolates. In this protocol the reductive cleavage of chalcogen bond by the Zn/NH4OH system led to zinc chalcogenolates. The reaction was carried out with acids and esters propiolics afford β-chalcogenacrillic acids and esters under mild and basic conditions. The stereochemistry corresponding to anti-Markovnikov addition of the chalcogenolate constituents across the triple bond were obtained in good yields. |